BNF for Children (BNFC) 2018-2019

Key to recommended regimens for prophylaxis against malaria

Codes for regimens Details of regimens for prophylaxis against malaria

• No risk

1 Chemoprophylaxis not recommended, but avoid mosquito bites and consider malaria if fever presents

2 Chloroquine only

3 Chloroquine with proguanil

4 Atovaquone with proguanil hydrochloride or doxycycline or mefloquine

Specific recommendations

Country Comments on risk of malaria and regional or seasonal variation Codes for regimens

Afghanistan Low risk below 2000 m from May–November 1

Very low risk below 2000 m from December–April 1

Algeria Very low risk in remote focus in Illizi department only 1

Andaman and Nicobar Islands
(India)

Low risk 1

Angola High risk 4

Argentina Very low risk in low altitude areas of Salta provinces bordering Bolivia and in Chaco,
Corrientes, and Misiones provinces close to border with Paraguay and Brazil

1

No risk in Iguaçu Falls and areas other than those above -

Armenia No risk 1

Azerbaijan Very low risk 1

Bangladesh High risk in Chittagong Hill Tract districts (but not Chittagong city) 4

Very low risk in Chittagong city and other areas, except Chittagong Hill Tract

districts

1

Belize Low risk in rural areas 1

No risk in Belize district (including Belize city and islands) -

Benin High risk 4

Bhutan Low risk in southern belt districts, along border with India: Chukha, Geyleg-phug,
Samchi, Samdrup Jonkhar, and Shemgang

1

No risk in areas other than those above -

Bolivia Low risk in Amazon basin 1

Low risk in rural areas below 2500 m (other than above) 1

No risk above 2500 m-

Botswana High risk from November–June in northern half, including Okavango Delta area 4

Low risk from July–October in northern half 1

Very low risk in southern half 1

Brazil Low risk in Amazon basin, including city of Manaus 1

Very low risk in areas other than those above 1

No risk in Iguaçu Falls -

Brunei Darussalam Very low risk 1

Burkina Faso High risk 4

Burundi High risk 4

Cambodia Low risk. Mefloquine resistance widespread in western provinces bordering
Thailand

1

Very low risk in Angkor Wat and Lake Tonle Sap, including Siem Reap 1

No risk in Phnom Penh -

Cameroon High risk 4

Cape Verde Very low risk on island of Santiago (Sao Tiago) and Boa Vista 1

Central African Republic High risk 4

Chad High risk 4

China Low risk in Yunnan and Hainan provinces 1

Very low risk in southern and some central provinces, including Anhui, Ghuizhou,

Hena, Hubei, and Jiangsu below 1500 m

1

Very low risk in areas other than those above and below 1

No risk in Hong Kong -

BNFC 2018 – 2019 Malaria 387

Infection

5