prescribed and dispensed by brand name, seeBiological
medicinesandBiosimilar medicines, under Guidance on
prescribing p. 1.
GENOTROPIN®PREPARATIONSCartridges are for use with
Genotropin®Pen device (non-NHS but available free of
charge from clinics).
NORDITROPIN®PREPARATIONSCartridges are for use with
appropriateNordiPen®device (non-NHS but available free
of charge from clinics).
Multidose disposable prefilled pens for use with
NovoFine®orNovoTwist®needles.
NUTROPINAQ®For use withNutropinAq®Pen device
(non-NHS but available free of charge from clinics).
OMNITROPE®For use withOmnitrope Pen 5 ®and
Omnitrope Pen 10 ®devices (non-NHS but available free of
charge from clinics).
SAIZEN®POWDER AND SOLVENT FOR SOLUTION FOR
INJECTIONFor use withone. click®autoinjector device or
cool.click®needle-free autoinjector device oreasypod®
autoinjector device (non-NHS but available free of charge
from clinics).
SAIZEN®SOLUTION FOR INJECTIONFor use with
cool.click®needle-free autoinjector device oreasypod®
autoinjector device (non-NHS but available free of charge
from clinics).
ZOMACTON® 4 mg vial for use withZomaJet 2 ®Vision
needle-free device (non-NHS but available free of charge
from clinics) or with needles and syringes.
10 mg vial for use withZomaJet Vision X®needle-free
device (non-NHS but available free of charge from clinics)
or with needles and syringes.
lNATIONAL FUNDING/ACCESS DECISIONS
NICE decisions
▶Somatropin for the treatment of growth failure in children
(May 2010 )NICE TA188
Somatropin is recommended for children with growth
failure who:
.have growth-hormone deficiency
.have Turner syndrome
.have Prader-Willi syndrome
.have chronic renal insufficiency
.are born small for gestational age with subsequent
growth failure at 4 years of age or later
.have short stature homeobox-containing gene (SHOX)
deficiency.
Treatment should be discontinued if growth velocity
increases by less than 50 % from baseline in thefirst year of
treatment.
http://www.nice.org.uk/TA188lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Solution for injection
EXCIPIENTS:May contain Benzyl alcohol
▶Norditropin NordiFlex(Novo Nordisk Ltd)
Somatropin (epr) 3.3 mg per 1 mlNorditropin NordiFlex 5 mg/ 1. 5 ml
solution for injection pre-filled pen| 1 pre-filled disposable
injectionP£ 115. 90 e
Somatropin (epr) 6.7 mg per 1 mlNorditropin NordiFlex
10 mg/ 1. 5 ml solution for injection pre-filled pen| 1 pre-filled
disposable injectionP£ 231. 80 e
Somatropin (epr) 10 mg per 1 mlNorditropin NordiFlex
15 mg/ 1. 5 ml solution for injection pre-filled pen| 1 pre-filled
disposable injectionP£ 347. 70 e
▶Norditropin SimpleXx(Novo Nordisk Ltd)
Somatropin (epr) 3.3 mg per 1 mlNorditropin SimpleXx 5 mg/ 1. 5 ml
solution for injection cartridges| 1 cartridgeP£ 106. 35 DT =
£ 106. 35 e
Somatropin (epr) 6.7 mg per 1 mlNorditropin SimpleXx
10 mg/ 1. 5 ml solution for injection cartridges| 1 cartridgeP
£ 212. 70 DT = £ 212. 70 eSomatropin (epr) 10 mg per 1 mlNorditropin SimpleXx 15 mg/ 1. 5 ml
solution for injection cartridges| 1 cartridgeP£ 319. 05 DT =
£ 319. 05 e
▶NutropinAq(Ipsen Ltd)
Somatropin (rbe) 5 mg per 1 mlNutropinAq 10 mg/ 2 ml solution for
injection cartridges| 1 cartridgeP£ 203. 00 e|
3 cartridgeP£ 609. 00 e
▶Omnitrope SurePal(Sandoz Ltd)
Somatropin (rbe) 3.333 mg per 1 mlOmnitrope SurePal 5
5 mg/ 1. 5 ml solution for injection cartridges| 5 cartridgeP
£ 368. 74 e
Somatropin (rbe) 6.667 mg per 1 mlOmnitrope SurePal 10
10 mg/ 1. 5 ml solution for injection cartridges| 5 cartridgeP
£ 737. 49 e
Somatropin (rbe) 10 mg per 1 mlOmnitrope SurePal 15
15 mg/ 1. 5 ml solution for injection cartridges| 5 cartridgeP
£ 1 , 106. 22 e
▶Saizen(Merck Serono Ltd)
Somatropin (rmc) 5.825 mg per 1 mlSaizen 6 mg/ 1. 03 ml solution
for injection cartridges| 1 cartridgeP£ 139. 08 DT =
£ 139. 08 e
Somatropin (rmc) 8 mg per 1 mlSaizen 20 mg/ 2. 5 ml solution for
injection cartridges| 1 cartridgeP£ 463. 60 DT = £ 463. 60 e
Saizen 12 mg/ 1. 5 ml solution for injection cartridges|
1 cartridgeP£ 278. 16 DT = £ 278. 16 e
Powder and solvent for solution for injection
EXCIPIENTS:May contain Benzyl alcohol
▶Genotropin(Pfizer Ltd)
Somatropin (rbe) 5.3 mgGenotropin 5. 3 mg powder and solvent for
solution for injection cartridges| 1 cartridgeP£ 92. 15 DT =
£ 92. 15 e
Somatropin (rbe) 12 mgGenotropin 12 mg powder and solvent for
solution for injection cartridges| 1 cartridgeP£ 208. 65 DT =
£ 208. 65 e
▶Genotropin GoQuick(Pfizer Ltd)
Somatropin (rbe) 5.3 mgGenotropin GoQuick 5. 3 mg powder and
solvent for solution for injection pre-filled disposable devices| 1 pre-
filled disposable injectionP£ 92. 15 DT = £ 92. 15 e
Somatropin (rbe) 12 mgGenotropin GoQuick 12 mg powder and
solvent for solution for injection pre-filled disposable devices| 1 pre-
filled disposable injectionP£ 208. 65 e
▶Genotropin MiniQuick(Pfizer Ltd)
Somatropin (rbe) 200 microgramGenotropin MiniQuick
200 microgram powder and solvent for solution for injection pre-filled
disposable devices| 7 pre-filled disposable injectionP£ 24. 35 DT
=£ 24. 35 e
Somatropin (rbe) 400 microgramGenotropin MiniQuick
400 microgram powder and solvent for solution for injection pre-filled
disposable devices| 7 pre-filled disposable injectionP£ 48. 68 DT
=£ 48. 68 e
Somatropin (rbe) 600 microgramGenotropin MiniQuick
600 microgram powder and solvent for solution for injection pre-filled
disposable devices| 7 pre-filled disposable injectionP£ 73. 03 DT
=£ 73. 03 e
Somatropin (rbe) 800 microgramGenotropin MiniQuick
800 microgram powder and solvent for solution for injection pre-filled
disposable devices| 7 pre-filled disposable injectionP£ 97. 37 DT
=£ 97. 37 e
Somatropin (rbe) 1 mgGenotropin MiniQuick 1 mg powder and
solvent for solution for injection pre-filled disposable devices| 7 pre-
filled disposable injectionP£ 121. 71 DT = £ 121. 71 e
Somatropin (rbe) 1.2 mgGenotropin MiniQuick 1. 2 mg powder and
solvent for solution for injection pre-filled disposable devices| 7 pre-
filled disposable injectionP£ 146. 06 DT = £ 146. 06 e
Somatropin (rbe) 1.4 mgGenotropin MiniQuick 1. 4 mg powder and
solvent for solution for injection pre-filled disposable devices| 7 pre-
filled disposable injectionP£ 170. 39 DT = £ 170. 39 e
Somatropin (rbe) 1.6 mgGenotropin MiniQuick 1. 6 mg powder and
solvent for solution for injection pre-filled disposable devices| 7 pre-
filled disposable injectionP£ 194. 74 DT = £ 194. 74 e
Somatropin (rbe) 1.8 mgGenotropin MiniQuick 1. 8 mg powder and
solvent for solution for injection pre-filled disposable devices| 7 pre-
filled disposable injectionP£ 219. 08 DT = £ 219. 08 e
Somatropin (rbe) 2 mgGenotropin MiniQuick 2 mg powder and
solvent for solution for injection pre-filled disposable devices| 7 pre-
filled disposable injectionP£ 243. 42 DT = £ 243. 42 e
▶Humatrope(Eli Lilly and Company Ltd)
Somatropin (rbe) 6 mgHumatrope 6 mg powder and solvent for
solution for injection cartridges| 1 cartridgeP£ 108. 00 e476 Hypothalamic and anterior pituitary hormone related disorders BNFC 2018 – 2019
Endocrine system6