BNF for Children (BNFC) 2018-2019

(singke) #1
▶Neonate: 0. 25 mL/kilogram twice daily, the total daily
dose may alternatively be given in 3 divided doses,
prophylactic iron supplementation may be required in
babies of low birth-weight who are solely breast-fed;
supplementation is started 4 – 6 weeks after birth and
continued until mixed feeding is established.

▶Child 1 month–11 years: 0. 25 mL/kilogram twice daily,
the total daily dose may alternatively be given in
3 divided doses, prophylactic iron supplementation
may be required in babies of low birth-weight who are
solely breast-fed; supplementation is started
4 – 6 weeks after birth and continued until mixed
feeding is established; maximum 20 mL per day
▶Child 12–17 years: 10 mL once daily
Iron-deficiency anaemia (therapeutic)
▶BY MOUTH
▶Neonate: 0. 25 mL/kilogram twice daily, the total daily
dose may alternatively be given in 3 divided doses.

▶Child 1 month–11 years: 0. 25 mL/kilogram twice daily,
the total daily dose may alternatively be given in
3 divided doses; maximum 20 mL per day
▶Child 12–17 years: 10 mL 1 – 2 times a day

lINTERACTIONS→Appendix 1 : iron (oral)
lSIDE-EFFECTSFaecal impaction.haemosiderosis
lPRESCRIBING AND DISPENSING INFORMATIONNon-
proprietary ferrous fumarate tablets may contain 210 mg
( 68 mg iron), syrup may contain approx. 140 mg ( 45 mg
iron)/ 5 mL;Galfer®capsules contain ferrous fumarate
305 mg ( 100 mg iron);Fersaday®tablets contain ferrous
fumarate 322 mg ( 100 mg iron).
lPATIENT AND CARER ADVICE
Medicines for Children leaflet: Ferrous fumarate for iron-deficiency
anaemiawww.medicinesforchildren.org.uk/ferrous-fumarate-
for-iron-deficiency-anaemia

lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Oral solution
▶Ferrous fumarate (Non-proprietary)
Ferrous fumarate 28 mg per 1 mlFerrous fumarate 140 mg/ 5 ml
oral solution| 200 mlp£ 3. 92 DT = £ 3. 92
▶Galfer(Thornton & Ross Ltd)
Ferrous fumarate 28 mg per 1 mlGalfer 140 mg/ 5 ml syrup sugar-
free| 300 mlp£ 5. 33 DT = £ 5. 33
Tablet
▶Ferrous fumarate (Non-proprietary)
Ferrous fumarate 210 mgFerrous fumarate 210 mg tablets|
84 tabletp£ 3. 50 DT = £ 3. 50 | 84 tabletsDT = £ 3. 50
Ferrous fumarate 322 mgFerrous fumarate 322 mg tablets|
28 tabletp£ 1. 00 DT = £ 1. 00
Capsule
▶Galfer(Thornton & Ross Ltd)
Ferrous fumarate 305 mgGalfer 305 mg capsules| 100 capsulep
£ 2. 33 DT = £ 2. 33 | 250 capsulep£ 5. 00
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Ferrous gluconate


lINDICATIONS AND DOSE
Prophylaxis of iron-deficiency anaemia
▶BY MOUTH USING TABLETS
▶Child 6–11 years: 300 – 900 mg daily
▶Child 12–17 years: 600 mg daily
Treatment of iron-deficiency anaemia
▶BY MOUTH USING TABLETS
▶Child 6–11 years: 300 – 900 mg daily
▶Child 12–17 years: 1. 2 – 1. 8 g daily in divided doses

lINTERACTIONS→Appendix 1 : iron (oral)
lSIDE-EFFECTSGastrointestinal disorders

lPRESCRIBING AND DISPENSING INFORMATIONFerrous
gluconate 300 mg contains 35 mg iron.
lPATIENT AND CARER ADVICE
Medicines for Children leaflet: Ferrous gluconate for iron-
deficiency anaemiawww.medicinesforchildren.org.uk/ferrous-
gluconate-for-iron-deficiency-anaemia

lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Tablet
▶Ferrous gluconate (Non-proprietary)
Ferrous gluconate 300 mgFerrous gluconate 300 mg tablets|
28 tabletp£ 3. 35 DT = £ 0. 64 | 1000 tabletp£ 15. 00 – £ 119. 64

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Ferrous sulfate 20-Jul-2017


lINDICATIONS AND DOSE
Iron-deficiency anaemia (prophylactic)
▶BY MOUTH USING TABLETS
▶Child 6–17 years: 200 mg daily
Iron-deficiency anaemia (therapeutic)
▶BY MOUTH USING TABLETS
▶Child 6–17 years: 200 mg 2 – 3 times a day
FEOSPAN®
Iron-deficiency anaemia
▶BY MOUTH
▶Child 1–17 years: 1 capsule daily, capsule can be opened
and sprinkled on food
FERROGRAD®
Iron-deficiency anaemia (prophylactic and therapeutic)
▶BY MOUTH
▶Child 12–17 years: 1 tablet daily
IRONORM®DROPS
Iron-deficiency anaemia (prophylactic)
▶BY MOUTH
▶Child 1 month–5 years: 0. 2 mL daily until mixed feeding
established, higher doses up to max. 0. 08 mL/kg daily
may be needed, then 0. 5 – 1. 2 mL daily
▶Child 6–11 years: 2. 4 mL daily
▶Child 12–17 years: 2. 4 – 4. 8 mL daily
Iron-deficiency anaemia (therapeutic)
▶BY MOUTH
▶Child 1 month–5 years: 0. 12 – 0. 24 mL/kilogram daily in
2 – 3 divided doses; maximum 8 mL per day
▶Child 6–11 years: 0. 12 – 0. 24 mL/kilogram daily in
2 – 3 divided doses; maximum 8 mL per day
▶Child 12–17 years: 4 mL 1 – 2 times a day

lINTERACTIONS→Appendix 1 : iron (oral)
lSIDE-EFFECTSTooth discolouration
lPRESCRIBING AND DISPENSING INFORMATION
Iron contentFerrous sulfate 200 mg is equivalent to 65 mg
iron;Ironorm®drops contain ferrous sulfate 125 mg
(equivalent to 25 mg iron)/mL;Feospan®spansules
contains ferrous sulfate 150 mg ( 47 mg iron) (spansule (=
capsules m/r));Ferrograd®tablets contain ferrous sulfate
325 mg ( 105 mg iron).
lPATIENT AND CARER ADVICE
Medicines for Children leaflet: Ferrous sulfate for iron-deficiency
anaemiawww.medicinesforchildren.org.uk/ferrous-sulfate-
iron-deficiency-anaemia
lNATIONAL FUNDING/ACCESS DECISIONS
NHS restrictionsFeospan®is not prescribable in NHS
primary care.
lLESS SUITABLE FOR PRESCRIBINGFeospan®is less suitable
for prescribing.Ferrograd®is less suitable for prescribing.

572 Anaemias BNFC 2018 – 2019


Blood and nutrition

9

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