lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Modified-release tablet
CAUTIONARY AND ADVISORY LABELS 25
▶Ferrograd(Teofarma)
Ferrous sulfate dried 325 mgFerrograd 325 mg modified-release
tablets| 30 tabletp£ 2. 58 DT = £ 2. 58
Tablet
▶Ferrous sulfate (Non-proprietary)
Ferrous sulfate dried 200 mgFerrous sulfate 200 mg tablets|
28 tabletp£ 8. 15 DT = £ 0. 95 | 60 tabletp£ 1. 78 – £ 3. 05 |
100 tabletp£ 3. 39 – £ 10. 80 | 1000 tabletp£ 38. 37 – £ 108. 00
Modified-release capsule
CAUTIONARY AND ADVISORY LABELS 25
▶Feospan Spansules(Intrapharm Laboratories Ltd)
Ferrous sulfate dried 150 mgFeospan 150 mg Spansules|
30 capsulep£ 3. 95
Oral drops
▶Ironorm(Wallace Manufacturing Chemists Ltd)
Ferrous sulfate 125 mg per 1 mlIronorm 125 mg/ml oral drops
sugar-free| 15 mlp£ 30. 00 DT = £ 30. 00
Ferrous sulfate with folic acid 20-Jul-2017
The properties listed below are those particular to the
combination only. For the properties of the components
please consider, ferrous sulfate p. 572 , folic acid p. 574.
lINDICATIONS AND DOSE
Iron-deficiency anaemia
▶BY MOUTH USING MODIFIED-RELEASE TABLETS
▶Child 12–17 years: 1 tablet daily, to be taken before food
lINTERACTIONS→Appendix 1 : folates.iron (oral)
lLESS SUITABLE FOR PRESCRIBINGFerrograd Folic®is less
suitable for prescribing.
lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Modified-release tablet
CAUTIONARY AND ADVISORY LABELS 25
▶Ferrograd Folic(Teofarma)
Folic acid 350 microgram, Ferrous sulfate dried
325 mgFerrograd Folic 325 mg/ 350 microgram modified-release
tablets| 30 tabletp£ 2. 64 DT = £ 2. 64
eiiiiF 571
Polysaccharide-iron complex 20-Jul-2017
lINDICATIONS AND DOSE
Iron-deficiency anaemia (prophylactic)
▶BY MOUTH
▶Neonate: 1 drop (approximately 500 micrograms iron)
per 450 g body-weight to be given 3 times a daily, dose
to be administered from dropper bottle, prophylactic
iron supplementation may be required in babies of low
birth-weight who are solely breast-fed;
supplementation is started 4 – 6 weeks after birth and
continued until mixed feeding is established.
▶Child 1 month–1 year: 1 drop (approximately
500 micrograms iron) per 450 g body-weight to be to be
given 3 times a daily, dose to be administered from
dropper bottle, prophylactic iron supplementation may
be required in babies of low birth-weight who are solely
breast-fed; supplementation is started 4 – 6 weeks after
birth and continued until mixed feeding is established
▶Child 12–17 years: 2. 5 mL daily
Iron-deficiency anaemia (therapeutic)
▶BY MOUTH
▶Child 2–5 years: 2. 5 mL daily
▶Child 6–11 years: 5 mL daily
▶Child 12–17 years: 5 mL 1 – 2 times a day
Iron-deficiency anaemia (therapeutic) if required during
second and third trimester of pregnancy
▶BY MOUTH
▶Child 12–17 years: 5 mL once daily
lINTERACTIONS→Appendix 1 : iron (oral)
lPATIENT AND CARER ADVICECounselling on the use of the
dropper advised.
lNATIONAL FUNDING/ACCESS DECISIONS
NHS restrictionsNiferex®elixir is not prescribable in NHS
primary care, except for the 30 -mL paediatric dropper
bottle for prophylaxis and treatment of iron deficiency in
infants born prematurely; endorse prescription‘SLS’.
lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Oral solution
▶Niferex(Tillomed Laboratories Ltd)
Iron (as Polysaccharide-iron complex) 100 mgNiferex 100 mg/ 5 ml
elixir sugar-free| 30 mlp£ 2. 16 sugar-free| 240 mlp£ 6. 06
eiiiiF 571
Sodium feredetate
(Sodium ironedetate)
lINDICATIONS AND DOSE
Iron-deficiency anaemia (therapeutic)
▶BY MOUTH USING ORAL SOLUTION
▶Neonate:Up to 2. 5 mL twice daily, smaller doses to be
used initially.
▶Child 1–11 months:Up to 2. 5 mL twice daily, smaller
doses to be used initially
▶Child 1–4 years: 2. 5 mL 3 times a day
▶Child 5–11 years: 5 mL 3 times a day
▶Child 12–17 years: 5 mL 3 times a day, increased to 10 mL
3 times a day, dose to be increased gradually
Iron-deficiency anaemia (prophylactic)
▶BY MOUTH USING ORAL SOLUTION
▶Neonate: 1 mL daily, prophylactic iron supplementation
may be required in babies of low birth-weight who are
solely breast-fed; supplementation is started 4 – 6 weeks
after birth and continued until mixed feeding is
established.
▶Child 1–11 months: 1 mL daily, prophylactic iron
supplementation may be required in babies of low
birth-weight who are solely breast-fed;
supplementation is started 4 – 6 weeks after birth and
continued until mixed feeding is established
lUNLICENSED USENot licensed for prophylaxis of iron
deficiency.
lINTERACTIONS→Appendix 1 : iron (oral)
lPRESCRIBING AND DISPENSING INFORMATIONSytron®
contains 207. 5 mg sodium feredetate trihydrate, which is
equivalent to 27. 5 mg of iron/ 5 mL.
lPATIENT AND CARER ADVICE
Medicines for Children leaflet: Sytron (sodium feredetate) for the
prevention of anaemiawww.medicinesforchildren.org.uk/
sytron-sodium-feredetate-for-prevention-of-anaemia
Medicines for Children leaflet: Sytron (sodium feredetate) for the
treatment of anaemiawww.medicinesforchildren.org.uk/sytron-
sodium-feredetate-for-treatment-of-anaemia
BNFC 2018 – 2019 Iron deficiency anaemia 573
Blood and nutrition
9