Vitamin B complex 20-Jul-2017
lINDICATIONS AND DOSE
Treatment of deficiency
▶BY MOUTH USING SYRUP
▶Child 1–11 months: 5 mL 3 times a day, this dose is for
Vigranon B®syrup.
▶Child 1–11 years: 10 mL 3 times a day, this dose is for
Vigranon B®syrup.
▶Child 12–17 years: 10 – 15 mL 3 times a day, this dose is
forVigranon B®syrup.
Prophylaxis of deficiency
▶BY MOUTH USING SYRUP
▶Child 1–11 months: 5 mL once daily, this dose is for
Vigranon B®syrup.
▶Child 1–11 years: 5 mL twice daily, this dose is for
Vigranon B®syrup.
▶Child 12–17 years: 5 mL 3 times a day, this dose is for
Vigranon B®syrup.lNATIONAL FUNDING/ACCESS DECISIONS
NHS restrictionsVigranon B®syrup is not prescribable in
NHS primary care.
lLESS SUITABLE FOR PRESCRIBINGVitamin B compound
tablets, vitamin B compound strong tablets, andVigranon
B®syrup are less suitable for prescribing.
lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Oral solution
▶Vigranon-B(Wallace Manufacturing Chemists Ltd)
Pyridoxine hydrochloride 400 microgram per 1 ml, Riboflavin
sodium phosphate 548 microgram per 1 ml, Dexpanthenol
600 microgram per 1 ml, Thiamine hydrochloride 1 mg per 1 ml,
Nicotinamide 4 mg per 1 mlVigranon-B syrup sugar-free|
150 mlp£ 26. 00
Vitamins with minerals and trace
elements
lINDICATIONS AND DOSE
FORCEVAL®CAPSULES
Vitamin and mineral deficiency and as adjunct in
synthetic diets
▶BY MOUTH
▶Child 12–17 years: 1 capsule daily, one hour after a meal
KETOVITE®LIQUID
Prevention of vitamin deficiency in disorders of
carbohydrate or amino-acid metabolism|Adjunct in
restricted, specialised, or synthetic diets
▶BY MOUTH
▶Child: 5 mL daily, dose adjusted according to condition,
diet, or age, use withKetovite®Tabletsfor complete
vitamin supplementation.
KETOVITE®TABLETS
Prevention of vitamin deficiency in disorders of
carbohydrate or amino-acid metabolism|Adjunct in
restricted, specialised, or synthetic diets
▶BY MOUTH
▶Child: 1 tablet 3 times a day, dose adjusted according to
condition, diet, or age, use withKetovite®Liquidfor
complete vitamin supplementation.lPRESCRIBING AND DISPENSING INFORMATIONTo avoid
potential toxicity, the content of all vitamin preparations,
particularly vitamin A, should be considered when used
together with other supplements.
lPATIENT AND CARER ADVICE
Medicines for Children leaflet: Multivitamin preparations for
vitamin deficiencywww.medicinesforchildren.org.uk/
multivitamin-preparations-vitamin-deficiency
KETOVITE®LIQUIDKetovite®liquid may be mixed with
milk, cereal, or fruit juice.
KETOVITE®TABLETSTablets may be crushed immediately
before use.lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Oral emulsion
▶Ketovite(Essential Pharmaceuticals Ltd)
Cyanocobalamin 2.5 microgram per 1 ml, Choline chloride 30 mg
per 1 ml, Ergocalciferol 80 unit per 1 ml, Vitamin A 500 unit per
1mlKetovite liquid sugar-free| 150 mlp£ 19. 10
Tablet
▶Ketovite(Essential Pharmaceuticals Ltd)
Biotin 170 microgram, Folic acid 250 microgram, Pyridoxine
hydrochloride 330 microgram, Acetomenaphthone
500 microgram, Riboflavin 1 mg, Thiamine hydrochloride 1 mg,
Calcium pantothenate 1.16 mg, Nicotinamide 3.3 mg, Alpha
tocopheryl acetate 5 mg, Ascorbic acid 16.6 mg, Inositol
50 mgKetovite tablets| 100 tabletP£ 9. 21
Capsule
▶Forceval(Alliance Pharmaceuticals Ltd)
Cyanocobalamin 3 microgram, Selenium 50 microgram, Biotin
100 microgram, Iodine 140 microgram, Chromium
200 microgram, Molybdenum 250 microgram, Folic acid
400 microgram, Thiamine 1.2 mg, Riboflavin 1.6 mg, Copper
2 mg, Pyridoxine 2 mg, Manganese 3 mg, Pantothenic acid 4 mg,
Potassium 4 mg, Tocopheryl acetate 10 mg, Iron 12 mg, Zinc
15 mg, Nicotinamide 18 mg, Magnesium 30 mg, Ascorbic acid
60 mg, Phosphorus 77 mg, Calcium 100 mg, Ergocalciferol
400 unit, Vitamin A 2500 unitForceval capsules| 15 capsulep
£ 4. 86 | 30 capsulep£ 8. 48 | 90 capsulep£ 25. 44VITAMINS AND TRACE ELEMENTS›VITAMIN C
Ascorbic acid
(Vitamin C)
lINDICATIONS AND DOSE
Treatment of scurvy
▶BY MOUTH
▶Child 1 month–3 years: 125 – 250 mg daily in 1 – 2 divided
doses
▶Child 4–11 years: 250 – 500 mg daily in 1 – 2 divided doses
▶Child 12–17 years: 0. 5 – 1 g daily in 1 – 2 divided doses
Adjunct to desferrioxamine (to enhance the excretion of
iron 1 month after treatment)
▶BY MOUTH
▶Child: 100 – 200 mg daily, to be taken 1 hour before food
Metabolic disorders|Tyrosinaemia type III|Transient
tyrosinaemia of the newborn|Glutathione synthase
deficiency|Hawkinsinuria
▶BY MOUTH
▶Neonate: 50 – 200 mg daily, dose to be adjusted as
necessary.▶Child: 200 – 400 mg daily in 1 – 2 divided doses, dose to
be adjusted as necessary, increased if necessary up to
1 g dailylUNLICENSED USENot licensed for metabolic disorders.
lCONTRA-INDICATIONSHyperoxaluria
lCAUTIONS
CAUTIONS, FURTHER INFORMATION
▶Iron overloadAscorbic acid should not be given to patients
with cardiac dysfunction.BNFC 2018 – 2019 Vitamin deficiency 629
Blood and nutrition9