BNF for Children (BNFC) 2018-2019

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lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Oral solution
CAUTIONARY AND ADVISORY LABELS 13
ELECTROLYTES:May contain Bicarbonate, chloride, potassium, sodium
▶Movicol(Norgine Pharmaceuticals Ltd)
Macrogol’ 3350 ’105 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreMovicol Liquid sugar-free|
500 mlp£ 5. 41 DT = £ 5. 41
Macrogol’ 3350 ’13.125 gram, Potassium 27 mmol per 1 litre,
Bicarbonate 85 mmol per 1 litre, Chloride 267 mmol per 1 litre,
Sodium 325 mmol per 1 litreMovicol Ready to Take oral solution
25 ml sachets sugar-free| 30 sachetp£ 7. 72
Powder
CAUTIONARY AND ADVISORY LABELS10, 13
ELECTROLYTES:May contain Bicarbonate, chloride, potassium, sodium
▶Macrogol 3350 with potassium chloride, sodium bicarbonate and
sodium chloride (Non-proprietary)
Macrogol’ 3350 ’52.5 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreMacrogol compound half-
strength oral powder sachets NPF sugar free sugar-free|
30 sachetPsDT = £ 4. 38
Macrogol’ 3350 ’105 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreMacrogol compound oral
powder sachets sugar free sugar-free| 20 sachetp£ 2. 63 – £ 4. 45
sugar-free| 30 sachetp£ 6. 68 DT = £ 3. 95
Macrogol compound oral powder sachets sugar free plain sugar-free|
20 sachetp£ 2. 63 sugar-free| 30 sachetp£ 3. 95 DT = £ 3. 95
▶CosmoCol(Stirling Anglian Pharmaceuticals Ltd)
Macrogol’ 3350 ’52.5 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreCosmoCol Paediatric oral
powder 6. 9 g sachets sugar-free| 30 sachetP£ 2. 99 DT = £ 4. 38
Macrogol’ 3350 ’105 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreCosmoCol Orange Lemon and
Lime oral powder sachets sugar-free| 30 sachetp£ 3. 95 DT = £ 3. 95
CosmoCol Plain oral powder sachets sugar-free| 30 sachetp£ 3. 95
DT = £ 3. 95
CosmoCol Orange Flavour oral powder sachets sugar-free|
20 sachetp£ 2. 75 sugar-free| 30 sachetp£ 3. 95 DT = £ 3. 95
CosmoCol Lemon and Lime Flavour oral powder sachets sugar-free|
20 sachetp£ 2. 75 sugar-free| 30 sachetp£ 3. 95 DT = £ 3. 95
▶Laxido(Galen Ltd)
Macrogol’ 3350 ’52.5 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreLaxido Paediatric Plain oral
powder 6. 9 g sachets sugar-free| 30 sachetP£ 2. 99 DT = £ 4. 38
Macrogol’ 3350 ’105 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreLaxido Orange oral powder
sachets sugar free sugar-free| 20 sachetp£ 2. 75 sugar-free|
30 sachetp£ 3. 95 DT = £ 3. 95
▶Molative(Mylan)
Macrogol’ 3350 ’52.5 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreMolative Paediatric oral powder
6. 9 g sachets sugar-free| 30 sachetP£ 4. 30 DT = £ 4. 38
Macrogol’ 3350 ’105 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreMolative oral powder 13. 8 g
sachets sugar-free| 20 sachetp£ 2. 85 sugar-free| 30 sachetp
£ 4. 27 DT = £ 3. 95 sugar-free| 50 sachetp£ 7. 17
▶Molaxole(Meda Pharmaceuticals Ltd)
Macrogol’ 3350 ’105 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreMolaxole oral powder sachets
sugar-free| 20 sachetp£ 3. 78 sugar-free| 30 sachetp£ 5. 68 DT =
£ 3. 95
▶Movicol(Norgine Pharmaceuticals Ltd)
Macrogol’ 3350 ’52.5 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreMovicol Paediatric Plain oral
powder 6. 9 g sachets sugar-free| 30 sachetP£ 4. 38 DT = £ 4. 38


Movicol Paediatric Chocolate oral powder 6. 9 g sachets sugar-free|
30 sachetP£ 4. 38 DT = £ 4. 38
Macrogol’ 3350 ’105 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreMovicol Plain oral powder 13. 7 g
sachets sugar-free| 30 sachetp£ 8. 11 DT = £ 3. 95 sugar-free|
50 sachetp£ 13. 49
Movicol Chocolate oral powder 13. 9 g sachets sugar-free|
30 sachetp£ 8. 11 DT = £ 3. 95
Movicol oral powder 13. 8 g sachets lemon & lime sugar-free|
20 sachetp£ 5. 41 sugar-free| 30 sachetp£ 8. 11 DT = £ 3. 95
sugar-free| 50 sachetp£ 13. 49
▶VistaPrep(Tillotts Pharma Ltd)
Macrogol’ 3350 ’105 gram per 1 litre, Potassium 5.4 mmol per
1 litre, Bicarbonate 17 mmol per 1 litre, Chloride 53 mmol per
1 litre, Sodium 65 mmol per 1 litreVistaPrep oral powder 110 g
sachets sugar-free| 4 sachetp£ 7. 92

Magnesium hydroxide


lINDICATIONS AND DOSE
Constipation
▶BY MOUTH
▶Child 3–11 years: 5 – 10 mL as required, dose to be given
mixed with water at bedtime
▶Child 12–17 years: 30 – 45 mL as required, dose to be
given mixed with water at bedtime

lCONTRA-INDICATIONSAcute gastro-intestinal conditions
lINTERACTIONS→Appendix 1 : magnesium
lHEPATIC IMPAIRMENTAvoid in hepatic coma if risk of
renal failure.
lRENAL IMPAIRMENTIncreased risk of toxicity in renal
impairment.
Dose adjustmentsAvoid or reduce dose.
lPRESCRIBING AND DISPENSING INFORMATIONWhen
prepared extemporaneously, the BP states Magnesium
Hydroxide Mixture, BP consists of an aqueous suspension
containing about 8 % hydrated magnesium oxide.

lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Oral suspension
▶Magnesium hydroxide (Non-proprietary)
Magnesium hydroxide 79 mg per 1 mlMagnesium hydroxide 7. 45 -
8. 35 % oral suspension BP| 500 mlG£ 5. 15 – £ 5. 31
Magnesium hydroxide 80 mg per 1 mlMagnesium hydroxide 8 %
oral suspension| 200 mlG£ 3. 22 DT = £ 3. 22 | 500 mlG
£ 7. 99 – £ 8. 05
▶Brands may include Phillips’Milk of Magnesia

Sodium acid phosphate with sodium


phosphate


lINDICATIONS AND DOSE
Constipation (using Phosphates Enema BP Formula B)|
Bowel evacuation before abdominal radiological
procedures, endoscopy, and surgery (using Phosphates
Enema BP Formula B)
▶BY RECTUM
▶Child 3–6 years: 45 – 65 mL once daily
▶Child 7–11 years: 65 – 100 mL once daily
▶Child 12–17 years: 100 – 128 mL once daily
FLEET®READY-TO-USE ENEMA
Constipation|Bowel evacuation before abdominal
radiological procedures|Bowel evacuation before
endoscopy|Bowel evacuation before surgery
▶BY RECTUM
▶Child 3–6 years: 40 – 60 mL once daily
▶Child 7–11 years: 60 – 90 mL once daily
▶Child 12–17 years: 90 – 118 mL once daily

BNFC 2018 – 2019 Constipation 43


Gastro-intestinal system

1

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