lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug. Forms available from special-order
manufacturers include: eye drops
Ear/eye drops solution
EXCIPIENTS:May contain Benzalkonium chloride
▶Gentamicin (Non-proprietary)
Gentamicin (as Gentamicin sulfate) 3 mg per 1 mlGentamicin
0. 3 % ear/eye drops| 10 mlP£ 2. 63 DT = £ 2. 47Tobramycin 22-Nov-2016
lINDICATIONS AND DOSE
Local treatment of infections
▶TO THE EYE
▶Child 1–17 years:Apply twice daily for 6 – 8 days
Local treatment of infections (severe infection)
▶TO THE EYE
▶Child 1–17 years:Apply 4 times a day forfirst day, then
apply twice daily for 5 – 7 dayslINTERACTIONS→Appendix 1 : aminoglycosideslMEDICINAL FORMS
No licensed medicines listedANTIBACTERIALS›MACROLIDES
Azithromycin
lINDICATIONS AND DOSE
Trachomatous conjunctivitis caused byChlamydia
trachomatis|Purulent bacterial conjunctivitis
▶TO THE EYE
▶Child:Apply twice daily for 3 days, review if no
improvement after 3 days of treatmentlINTERACTIONS→Appendix 1 : macrolides
lSIDE-EFFECTS
▶Common or very commonEye discomfort.vision blurred
▶UncommonAngioedema.eye allergylMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Eye drops
▶Azyter(Thea Pharmaceuticals Ltd)
Azithromycin dihydrate 15 mg per 1 gramAzyter 15 mg/g eye
drops 0. 25 g unit dose| 6 unit doseP£ 6. 99 DT = £ 6. 99ANTIBACTERIALS›QUINOLONES
Ciprofloxacin 26-Apr-2018
lINDICATIONS AND DOSE
Superficial bacterial eye infection
▶TO THE EYE USING EYE DROP
▶Child:Apply 4 times a day for maximum duration of
treatment 21 days
▶TO THE EYE USING EYE OINTMENT
▶Child 1–17 years:Apply 1. 25 centimetres 3 times a day
for 2 days, then apply 1. 25 centimetres twice daily for
5 days
Superficial bacterial eye infection (severe infection)
▶TO THE EYE USING EYE DROP
▶Child:Apply every 2 hours during waking hours for
2 days, then apply 4 times a day for maximum duration
of treatment 21 daysCorneal ulcer
▶TO THE EYE USING EYE DROP
▶Child:Apply every 15 minutes for 6 hours, then apply
every 30 minutes for the remainder of day 1 , then apply
every 1 hour on day 2 , then apply every 4 hours on days
3 – 14 , maximum duration of treatment 21 days, to be
administered throughout the day and night
▶TO THE EYE USING EYE OINTMENT
▶Child 1–17 years:Apply 1. 25 centimetres every
1 – 2 hours for 2 days, then apply 1. 25 centimetres every
4 hours for the next 12 days, to be administered
throughout the day and nightlUNLICENSED USEEye ointment not licensed for use in
children under 1 year.
lINTERACTIONS→Appendix 1 : quinolones
lSIDE-EFFECTS
▶Common or very commonCorneal deposits (reversible after
completion of treatment)
▶UncommonEye disorders.eye inflammation.eyelid
crusting.vision disorders
▶Rare or very rareDermatitis.ear pain.increased risk of
infection.paranasal sinus hypersecretion
▶Frequency not knownTendon disorder
lPREGNANCYManufacturer advises use only if potential
benefit outweighs risk.
lBREAST FEEDINGManufacturer advises caution.lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug. Forms available from special-order
manufacturers include: eye drops
Eye drops
EXCIPIENTS:May contain Benzalkonium chloride
▶Ciloxan(Novartis Pharmaceuticals UK Ltd)
Ciprofloxacin (as Ciprofloxacin hydrochloride) 3 mg per
1mlCiloxan 0. 3 % eye drops| 5 mlP£ 4. 70 DT = £ 4. 70Levofloxacin 13-Jul-2017
lINDICATIONS AND DOSE
Local treatment of eye infections
▶TO THE EYE
▶Child 1–17 years:Apply every 2 hours forfirst 2 days, to
be applied maximum 8 times a day, then apply 4 times
a day for 3 dayslINTERACTIONS→Appendix 1 : quinolones
lSIDE-EFFECTS
▶Common or very commonEye discomfort
▶UncommonEye disorders.rhinitis
▶Rare or very rareLaryngeal oedema
lPREGNANCYManufacturer advises use only if potential
benefit outweighs risk.
lBREAST FEEDINGManufacturer advises use only if
potential benefit outweighs risk.
lPRESCRIBING AND DISPENSING INFORMATIONAlthough
multi-dose levofloxacin eye drops commonly contain
preservatives, preservative-free unit dose vials may be
available.lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Eye drops
EXCIPIENTS:May contain Benzalkonium chloride
▶Levofloxacin (Non-proprietary)
Levofloxacin (as Levofloxacin hemihydrate) 5 mg per
1mlLevofloxacin 5 mg/ml eye drops| 5 mlP£ 6. 95 DT = £ 6. 95676 Eye infections BNFC 2018 – 2019
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