lCONTRA-INDICATIONSPatent grommet (although may be
used by specialists, see Ear p. 688 ).perforated tympanic
membrane (although may be used by specialists, see Ear
p.^688 )
lCAUTIONSAvoid prolonged use
lSIDE-EFFECTSParaesthesia.skin reactions
lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Spray
EXCIPIENTS:May contain Hydroxybenzoates (parabens)
▶Otomize(Teva UK Ltd)
Dexamethasone 1 mg per 1 gram, Neomycin sulfate 5 mg per
1 gram, Acetic acid glacial 20 mg per 1 gramOtomize ear spray|
5 mlP£ 3. 27
Hydrocortisone with neomycin and
polymyxin B sulfate 21-Dec-2017
The properties listed below are those particular to the
combination only. For the properties of the components
please consider, neomycin sulfate p. 690.
lINDICATIONS AND DOSE
Bacterial infection in otitis externa
▶TO THE EAR
▶Child 3–17 years:Apply 3 drops 3 – 4 times a day for
7 days (review treatment if there is no clinical
improvement)IMPORTANT SAFETY INFORMATION
MHRA/CHM ADVICE: CORTICOSTEROIDS: RARE RISK OF CENTRAL
SEROUS CHORIORETINOPATHY WITH LOCAL AS WELL AS SYSTEMIC
ADMINISTRATION (AUGUST 2017)
See Corticosteroids, general use p. 434.lRENAL IMPAIRMENTManufacturer advises avoid
prolonged, unsupervised use.
Dose adjustmentsManufacturer advises reduce dose.
lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Ear drops
EXCIPIENTS:May contain Cetostearyl alcohol (including cetyl and
stearyl alcohol), hydroxybenzoates (parabens), polysorbates
▶Otosporin(Phoenix Labs Ltd)
Hydrocortisone 10 mg per 1 ml, Neomycin sulfate 3400 unit per
1 ml, Polymyxin B sulfate 10000 unit per 1 mlOtosporin ear drops
| 10 mlP£ 7. 45
DERMATOLOGICAL DRUGS›ASTRINGENTS
Aluminium acetate
lINDICATIONS AND DOSE
Inflammation in otitis externa
▶TO THE EAR
▶Child:To be inserted into meatus or apply on a ribbon
gauze dressing or sponge wick which should be kept
saturated with the ear dropslUNLICENSED USENot licensed for use in children.
lDIRECTIONS FOR ADMINISTRATIONFor ear drops 8 %—
dilute 8 parts aluminium acetate ear drops ( 13 %) with
5 parts purified water. Must be freshly prepared.
lMEDICINAL FORMS
Forms available from special-order manufacturers include: ear
drops
2 Removal of earwax
BICARBONATE
Sodium bicarbonate
lINDICATIONS AND DOSE
Removal of earwax (with 5 % ear drop solution)
▶TO THE EAR
▶Child:(consult product literature)lSIDE-EFFECTSDry earlMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug. Forms available from special-order
manufacturers include: capsule, oral suspension, oral solution,
solution for injection, liquid, mouthwash
Ear drops
▶Sodium bicarbonate (Non-proprietary)
Sodium bicarbonate 50 mg per 1 mlSodium bicarbonate 5 % ear
drops| 10 ml £ 1. 23 – £ 1. 25SOFTENING DRUGS
Almond oil
lINDICATIONS AND DOSE
Removal of earwax
▶TO THE EAR
▶Child:Allow drops to warm to room temperature before
use (consult product literature)lDIRECTIONS FOR ADMINISTRATIONThe patient should lie
with the affected ear uppermost for 5 to 10 minutes after a
generous amount of the softening remedy has been
introduced into the ear.lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Liquid
▶Almond oil (Non-proprietary)
Almond oil 1 ml per 1 mlAlmond oil liquid| 50 ml £ 0. 95 DT = £ 0. 95
| 70 ml £ 0. 85 | 200 ml £ 2. 68 | 500 ml £ 11. 90Arachis oil with chlorobutanol
lINDICATIONS AND DOSE
Removal of earwax
▶TO THE EAR
▶Child 1–17 years:(consult product literature)lLESS SUITABLE FOR PRESCRIBINGArachis (peanut) oil with
chlorobutanol ear drops are less suitable for prescribing.lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Ear drops
▶Cerumol(Thornton & Ross Ltd)
Chlorobutanol 50 mg per 1 ml, Arachis oil 573 mg per
1mlCerumol ear drops| 11 mlp£ 2. 05BNFC 2018 – 2019 Removal of earwax 693
Ear, nose and oropharynx12