BNF for Children (BNFC) 2018-2019

23 -valent pneumococcal polysaccharide vaccine should be

given after the second birthday. The influenza vaccine

should be administered annually in children aged 6 months

or older.

Childrenfirst diagnosed between 1 and 2 years of ageshould

be vaccinated according to the Immunisation Schedule,

including the 12 month boosters. Two months after the

routine 12 month booster vaccines, give a dose of

meningococcal groups A with C and W 135 and Y vaccine and

an additional dose of 13 -valent pneumococcal

polysaccharide vaccine. An additional dose of haemophilus

influenzae type b with meningococcal group C vaccine and

23 -valent pneumococcal polysaccharide vaccine should be

given after the second birthday. The influenza vaccine

should be administered annually.

Childrenfirst diagnosed over 2 years of ageshould be

vaccinated according to the Immunisation schedule,

including the 12 month boosters. The child should receive

one additional booster dose of haemophilus influenzae type

b with meningococcal group C vaccine along with the

23 -valent pneumococcal polysaccharide vaccine, followed by

one dose of meningococcal groups A with C and W 135 and Y

vaccine after 2 months. The influenza vaccine should be

administered annually.

Passive immunity

Immunity with immediate protection against certain

infective organisms can be obtained by injecting

preparations made from the plasma of immune individuals

with adequate levels of antibody to the disease for which

Routine immunisation schedule

When to immunise (for preterm infants-see

note above)

Vaccine given and dose schedule ( for details of dose, see under individual vaccines)

Neonates at risk only

▶Bacillus Calmette-Guérin vaccine p. 790 (at birth, seeBCG vaccine, below)

▶Hepatitis B vaccine p. 796 (at birth, seeHepatitis Bvaccine, below)

2 months ▶Diphtheria with tetanus, pertussis, hepatitis B, poliomyelitis and haemophilus influenzae

type b vaccine p. 790 (Infanrix hexa®). First dose

▶Meningococcal group B vaccine (rDNA, component, adsorbed) p. 792 First dose

▶Pneumococcal polysaccharide conjugate vaccine (adsorbed) p. 793 First dose

▶Rotavirus vaccine p. 801 First dose

3 months ▶Diphtheria with tetanus, pertussis, hepatitis B, poliomyelitis and haemophilus influenzae

type b vaccine p. 790 (Infanrix hexa®). Second dose

▶Rotavirus vaccine p. 801 Second dose

4 months ▶Diphtheria with tetanus, pertussis, hepatitis B, poliomyelitis and haemophilus influenzae

type b vaccine p. 790 (Infanrix hexa®). Third dose

▶Meningococcal group B vaccine (rDNA, component, adsorbed) p. 792 Second dose

▶Pneumococcal polysaccharide conjugate vaccine (adsorbed) p. 793 Second dose

12 – 13 months ▶Measles, mumps and rubella vaccine, live p. 799 First dose

▶Meningococcal group B vaccine (rDNA, component, adsorbed) p. 792 Single booster dose

▶Pneumococcal polysaccharide conjugate vaccine (adsorbed) p. 793 Single booster dose

▶Haemophilus influenzae type b with meningococcal group C vaccine p. 791 Single booster

dose

2 – 8 years (including children in school years

1 , 2 , 3 and 4 )

▶Influenza vaccine p. 798 Each year from September.Note: Flu nasal spray is recommended

(Fluenz Tetra®). If contra-indicated and child is in clinical risk group, use inactivated flu

vaccine

Between 3 years and 4 months, and 5 years ▶Diphtheria with pertussis, poliomyelitis vaccine and tetanus p. 789 Single booster dose.

Note: Preferably allow interval of at least 3 years after completing primary course

▶Measles, mumps and rubella vaccine, live p. 799 Second dose

11 – 14 years (females only). First dose of

HPV vaccine will be offered to females aged

12 – 13 years of age in England, Wales, and

Northern Ireland, and 11 – 13 years of age in

Scotland.

▶Human papillomavirus vaccines p. 797 Two doses; second dose 6 – 24 months after first

dose. If a 3 -dose course of HPV vaccine has been started under the 2013 / 2014 programme,

where possible, the course should be completed ( 2 doses less than 6 months apart does

not provide long-term protection). The two human papillomavirus vaccines are not

interchangeable and, ideally, one vaccine product should be used for the entire course.

However, since 2012 , onlyGardasil®is offered as part of the national immunisation

programme; for those females who started the schedule withCervarix®under the national

immunisation programme, but did not complete the vaccination course, the course can be

completed withGardasil®.

13 – 15 years ▶Meningococcal groups A with C and W 135 and Y vaccine p. 792 Single booster dose

13 – 18 years ▶Diphtheria with poliomyelitis and tetanus vaccine p. 790 Single booster dose.Note: Can be

given at the same time as the booster dose of meningococcal group A with C and W 135 and

Y vaccine at 13 – 15 years of age

During adult life, women of child-bearing

age susceptible to rubella

▶Measles, mumps and rubella vaccine, live p. 799 Women of child-bearing age who have not

received 2 doses of a rubella-containing vaccine or who do not have a positive antibody

test for rubella should be offered rubella immunisation (using the MMR vaccine)—exclude

pregnancy before immunisation.

Pregnant females ▶Acellular pertussis-containing vaccine administered as diphtheria with pertussis,

poliomyelitis vaccine and tetanus p. 789 (Boostrix-IPV®) 1 dose from the 16 th week of

pregnancy, preferably after the fetal anomaly scan (weeks 18 – 20 )

▶Influenza vaccine (inactivated) p. 798 , Single dose administered from September,

regardless of the stage of pregnancy

778 Vaccination BNFC 2018 – 2019

Vaccines

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