BNF for Children (BNFC) 2018-2019

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lPRESCRIBING AND DISPENSING INFORMATIONAvailable as
part of the childhood immunisation schedule from
ImmForm.

lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Powder and solvent for solution for injection
▶Menitorix(GlaxoSmithKline UK Ltd)
Menitorix vaccine powder and solvent for solution for injection 0. 5 ml
vials| 1 vialP£ 37. 76
eiiiiF 788

Meningococcal group B vaccine (rDNA,


component, adsorbed) 19-Oct-2017


lINDICATIONS AND DOSE
BEXSERO®
Immunisation againstNeisseria meningitidis, primary
immunisation
▶BY DEEP INTRAMUSCULAR INJECTION
▶Child 2 months: 0. 5 mL for 1 dose, injected preferably
into deltoid region (or anterolateral thigh in infants),
for information about the use of paracetamol for
prophylaxis of post-immunisation pyrexia, see
paracetamol p. 271.
▶Child 4 months: 0. 5 mL for 1 dose, injected preferably
into deltoid region (or anterolateral thigh in infants),
for information about the use of paracetamol for
prophylaxis of post-immunisation pyrexia, see
paracetamol p. 271.
Immunisation againstNeisseria meningitidis, primary
immunisation booster dose
▶BY DEEP INTRAMUSCULAR INJECTION
▶Child 12–23 months: 0. 5 mL for 1 dose, injected
preferably into deltoid region (or anterolateral thigh in
infants)
Immunisation againstNeisseria meningitidis, primary
immunisation (in unimmunised patients)
▶BY DEEP INTRAMUSCULAR INJECTION
▶Child 6–11 months: 0. 5 mL for 2 doses, separated by an
interval of at least 2 months; booster dose of 0. 5 mL
given between 1 – 2 years of age and at least 2 months
after completion of primary immunisation, injected
preferably into deltoid region (or anterolateral thigh in
infants)
▶Child 12–23 months: 0. 5 mL for 2 doses, separated by an
interval of at least 2 months; booster dose of 0. 5 mL
given 12 – 24 months after completion of primary
immunisation, injected preferably into deltoid region
(or anterolateral thigh in infants)
▶Child 2–10 years: 0. 5 mL for 2 doses, separated by an
interval of at least 2 months. Injected preferably into
deltoid region (or anterolateral thigh in infants)
▶Child 11–17 years: 0. 5 mL for 2 doses, separated by an
interval of at least 1 month. Injected preferably into
deltoid region
TRUMENBA®
Immunisation againstNeisseria meningitidis, primary
immunisation
▶BY INTRAMUSCULAR INJECTION
▶Child 10–17 years: 0. 5 mL for 2 doses, separated by an
interval of 6 months, alternatively 0. 5 mL for 2 doses,
separated by an interval of at least 1 month, followed
by 0. 5 mL as a third dose, given at least 4 months after
the second dose, injected preferably into deltoid
region, a booster dose should be considered for
individuals at continued risk—consult product
literature

lSIDE-EFFECTS
▶Common or very commonCrying abnormal.drowsiness.
eating disorder
▶UncommonEczema.seizures.vascular disorders
▶Frequency not knownExtensive swelling of vaccinated limb
.hypotonic-hyporesponsiveness episode

lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Suspension for injection
EXCIPIENTS:May contain Kanamycin
▶Bexsero(GlaxoSmithKline UK Ltd)A
Bexsero vaccine suspension for injection 0. 5 ml pre-filled syringes|
1 pre-filled disposable injectionP£ 75. 00
▶Trumenba(Pfizer Ltd)A
Trumenba vaccine suspension for injection 0. 5 ml pre-filled syringes|
1 pre-filled disposable injectionP£ 75. 00
eiiiiF 788

Meningococcal group C vaccine


lINDICATIONS AND DOSE
Patients with confirmed serogroup C disease (who have
previously been immunised)
▶BY INTRAMUSCULAR INJECTION
▶Child 1–17 years: 0. 5 mL for 1 dose, dose to be given
before discharge from hospital

lSIDE-EFFECTS
▶Common or very commonAnxiety.cough.crying.
drowsiness.gastrointestinal discomfort.hyperhidrosis.
increased risk of infection
▶UncommonChills.eyelid oedema.flushing.joint stiffness
▶Rare or very rareCirculatory collapse.influenza like
illness
▶Frequency not knownAngioedema.apnoea.asthenia.
dyspnoea.hypotonic-hyporesponsiveness episode.
immune thrombocytopenic purpura.meningism (but no
evidence that vaccine causes meningococcal C meningitis)
.musculoskeletal stiffness.nasal congestion.oedema.
pain.respiratory disorders.seizures.sensation abnormal.
sleep disorders.Stevens-Johnson syndrome.syncope
lPRESCRIBING AND DISPENSING INFORMATIONAvailable as
part of childhood immunisation schedule from
http://www.immform.dh.gov.uk.

lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Suspension for injection
▶NeisVac-C(Pfizer Ltd)
NeisVac-C vaccine suspension for injection 0. 5 ml pre-filled syringes|
10 pre-filled disposable injectionP£ 187. 50
eiiiiF 788

Meningococcal groups A with C and


W135 and Y vaccine


lINDICATIONS AND DOSE
MENVEO®
Primary immunisation againstNeisseria meningitidis
▶BY INTRAMUSCULAR INJECTION
▶Child 13–15 years: 0. 5 mL for 1 dose, dose preferably
injected into deltoid region
Immunisation againstNeisseria meningitidisin an
unimmunised patient
▶BY INTRAMUSCULAR INJECTION
▶Child 10–17 years: 0. 5 mL for 1 dose, booster dose is not
required

792 Vaccination BNFC 2018 – 2019


Vaccines

14

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