BNF for Children (BNFC) 2018-2019

lMEDICINAL FORMS

There can be variation in the licensing of different medicines

containing the same drug.

Suspension for injection

EXCIPIENTS:May contain Neomycin

▶ViATIM(Sanofi Pasteur)

ViATIM vaccine suspension for injection 1 ml pre-filled syringes| 1 pre-

filled disposable injectionP£ 35. 76

eiiiiF 788

Hepatitis B vaccine

lINDICATIONS AND DOSE

ENGERIX B®

Immunisation against hepatitis B infection

▶BY INTRAMUSCULAR INJECTION

▶Neonate: 10 micrograms for 1 dose, then 10 micrograms

after 1 month for 1 dose, followed by 10 micrograms

after 5 months for 1 dose, anterolateral thigh is

preferred site in neonates; not to be injected into the

buttock (vaccine efficacy reduced), this dose should not

be given to neonates born to hepatitis B surface antigen

positive mother.

▶Child 1 month–15 years: 10 micrograms for 1 dose, then

10 micrograms after 1 month for 1 dose, followed by

10 micrograms after 5 months for 1 dose, deltoid

muscle is preferred site of injection in older children;

anterolateral thigh is preferred site in infants and

young children; not to be injected into the buttock

(vaccine efficacy reduced)

▶Child 16–17 years: 20 micrograms for 1 dose, then

20 micrograms after 1 month for 1 dose, followed by

20 micrograms after 5 months for 1 dose, deltoid

muscle is preferred site of injection; not to be injected

into the buttock (vaccine efficacy reduced)

Immunisation against hepatitis B infection (accelerated

schedule)

▶BY INTRAMUSCULAR INJECTION

▶Neonate: 10 micrograms every month for 3 doses,

followed by 10 micrograms after 10 months for 1 dose,

anterolateral thigh is preferred site in neonates; not to

be injected into the buttock (vaccine efficacy reduced),

this dose should not be given to neonates born to

hepatitis B surface antigen positive mother.

▶Child 1 month–15 years: 10 micrograms every month for

3 doses, followed by 10 micrograms after 10 months for

1 dose, deltoid muscle is preferred site of injection in

older children; anterolateral thigh is preferred site in

infants and young children; not to be injected into the

buttock (vaccine efficacy reduced)

▶Child 16–17 years: 20 micrograms every month for

3 doses, followed by 20 micrograms after 10 months for

1 dose, deltoid muscle is preferred site of injection; not

to be injected into the buttock (vaccine efficacy

reduced)

Immunisation against hepatitis B infection, alternative

accelerated schedule

▶BY INTRAMUSCULAR INJECTION

▶Child 11–15 years: 20 micrograms for 1 dose, followed by

20 micrograms after 6 months, this schedule is not

suitable if high risk of infection between doses or if

compliance with second dose uncertain, deltoid muscle

is preferred site of injection; not to be injected into the

buttock (vaccine efficacy reduced)

Immunisation against hepatitis B infection (for neonates

born to hepatitis B surface antigen positive mother)

▶BY INTRAMUSCULAR INJECTION

▶Neonate: 10 micrograms once a month for 3 doses,first

dose to be given at birth with hepatitis B

immunoglobulin injection (separate site), followed by

10 micrograms after 10 months for 1 dose, anterolateral

thigh is preferred site in neonates; not to be injected

into the buttock (vaccine efficacy reduced).

Immunisation against hepatitis B infection (in renal

insufficiency, including haemodialysis patients)

▶BY INTRAMUSCULAR INJECTION

▶Neonate: 10 micrograms every month for 2 doses,

followed by 10 micrograms after 5 months for 1 dose,

immunisation schedule and booster doses may need to

be adjusted in those with low antibody concentration,

anterolateral thigh is preferred site in neonates; not to

be injected into the buttock (vaccine efficacy reduced),

this dose should not be given to neonates born to

hepatitis B surface antigen positive mother.

▶Child 1 month–15 years: 10 micrograms every month for

2 doses, followed by 10 micrograms after 5 months for

1 dose, immunisation schedule and booster doses may

need to be adjusted in those with low antibody

concentration, deltoid muscle is preferred site of

injection in older children; anterolateral thigh is

preferred site in infants and young children; not to be

injected into the buttock (vaccine efficacy reduced)

▶Child 16–17 years: 40 micrograms every month for

3 doses, followed by 40 micrograms after 4 months for

1 dose, immunisation schedule and booster doses may

need to be adjusted in those with low antibody

concentration, deltoid muscle is preferred site of

injection; not to be injected into the buttock (vaccine

efficacy reduced)

Immunisation against hepatitis B infection (in renal

insufficiency, including haemodialysis patients

(accelerated schedule))

▶BY INTRAMUSCULAR INJECTION

▶Neonate: 10 micrograms every month for 3 doses,

followed by 10 micrograms after 10 months for 1 dose,

immunisation schedule and booster doses may need to

be adjusted in those with low antibody concentration,

anterolateral thigh is preferred site in neonates; not to

be injected into the buttock (vaccine efficacy reduced),

this dose should not be given to neonates born to

hepatitis B surface antigen positive mother.

▶Child 1 month–15 years: 10 micrograms every month for

3 doses, followed by 10 micrograms after 10 months for

1 dose, immunisation schedule and booster doses may

need to be adjusted in those with low antibody

concentration, deltoid muscle is preferred site of

injection in older children; anterolateral thigh is

preferred site in infants and young children; not to be

injected into the buttock (vaccine efficacy reduced)

FENDRIX®

Immunisation against hepatitis B infection in renal

insufficiency (including pre-haemodialysis and

haemodialysis patients)

▶BY INTRAMUSCULAR INJECTION

▶Child 15–17 years: 20 micrograms every month for

3 doses, followed by 20 micrograms after 4 months for

1 dose, immunisation schedule and booster doses may

need to be adjusted in those with low antibody

concentration, deltoid muscle is preferred site of

injection; not to be injected into the buttock (vaccine

efficacy reduced)

HBVAXPRO®

Immunisation against hepatitis B infection

▶BY INTRAMUSCULAR INJECTION

▶Neonate: 5 micrograms for 1 dose, followed by

5 micrograms after 1 month for 1 dose, then

796 Vaccination BNFC 2018 – 2019

Vaccines

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