MCAT Organic Chemistry Review 2018-2019

(singke) #1

Before you move on, assess your understanding of the material with these questions.


How do  the definitions of  nucleophile and electrophile    differ  from    those   of  Lewis   base    and
acid?

What    are the four    main    trends  that    determine   nucleophilicity?

How must    the nucleophile and leaving group   be  related in  order   for a   substitution    reaction
to proceed?

What    trends  increase    electrophilicity?
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