Chapter Profile
The content in this chapter should be relevant to about 10% of all questions about Organic
Chemistry on the MCAT.
This chapter covers material from the following AAMC content category:
5D: Structure, function, and reactivity of biologically-relevant molecules
Introduction
Carboxylic acids, with both carbonyl and hydroxyl groups, are some of the most reactive organic
molecules you’ll encounter on Test Day. As we will see in this chapter, these molecules can react as
acids (as their name suggests), nucleophiles, and electrophiles, and are integral to many biological
processes. Carboxylic acids are found in soaps, oils, preservatives, skin care products, clothing, and
—most importantly for the MCAT—amino acids. Carboxylic acids often have strong, unpleasant