USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

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RUBELLA IGG ANTIBODY


Immunity:   The presence    of  rubella antibodies  rules   out a   primary infection
during the pregnancy. Antibodies derived from a natural, wild infection lead
to lifelong immunity. Antibodies from a live-attenuated virus are not as
durable.
Susceptibility: An absence of antibodies leaves the woman at risk for a
primary rubella infection in pregnancy that can have devastating fetal effects,
particularly in the first trimester. Rubella immunization is contraindicated in
pregnancy because it is made from a live virus but is recommended after
delivery.

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