USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

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Table I-7-1. Syphilis   in  Pregnancy

Characteristic Primary Secondary


Classic lesion Chancre Condyloma lata (“money spots”)


Extent of disease Localized Systemic


VDRL    (–)
Darkfield (+)
FTA-ABS (+)

VDRL    (+)
Darkfield (+)
FTA-ABS (+)

Fetal infection rate 60% 60%


Treatment of choice Penicillin Penicillin


Figure I-7-2. Maternal  Syphilis

ataxia),    or  bone    (osteitis). Not only    are the blood   tests   positive,   but also    the
cerebrospinal fluid will be positive with CNS involvement.

Lab tests (VDRL, Darkfield, FTA-ABS)


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