USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

(Kiana) #1

PARAMESONEPHRIC (MÜLLERIAN) DUCT


This duct is present in all early embryos and is the primordium of the female
internal reproductive system. No hormonal stimulation is required.


In  males,  the Y   chromosome  induces gonadal secretion   of  müllerian
inhibitory factor (MIF), which causes the müllerian duct to involute.
In females, without MIF, development continues to form the fallopian tubes,
corpus of the uterus, cervix, and proximal vagina.
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