USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

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MESONEPHRIC (WOLFFIAN) DUCT


This duct is also present in all early embryos and is the primordium of the male
internal reproductive system. Testosterone stimulation is required for
development to continue to form the vas deferens, seminal vesicles, epididymis,
and efferent ducts. This is present in males from testicular sources. In females,
without androgen stimulation, the Wolffian duct undergoes regression. If a
genetic male has an absence of androgen receptors, the Wolffian duct will also
undergo regression.

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