VAGINAL DISCHARGE
A 25-year-old woman complains of a whitish vaginal discharge. She states
that this is the first time she has this complaint, and it is associated with
vaginal and vulvar pruritus. There is no significant medical history, and she
is not on oral contraception.
Diagnostic Tests
Visual inspection: The vulva and vagina should be examined for evidence of
an inflammatory response as well as the gross characteristics of the vaginal
discharge seen on speculum examination.
Vaginal pH: Normal vaginal pH is an acidic <4.5. Identification of the pH is
easily performed using pH-dependent Nitrazine paper. Normal vaginal
discharge leaves the paper yellow, whereas an elevated pH turns the paper
dark.
Microscopic examination: Two drops of the vaginal discharge are placed on
a glass slide with a drop of normal saline placed on one, and a drop of KOH
placed on the other. The two sites are covered with cover slips and examined
under the microscope for WBC, pseudohyphae, trichomonads, and clue cells.