USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

(Kiana) #1

INFERTILITY


A   30-year-old woman   comes   to  the gynecologist’s  office  complaining of
infertility for one year. She and her husband have been trying to achieve
pregnancy for more than a year and have been unsuccessful. There is no
previous history of pelvic inflammatory disease and she used oral
contraception medication for six years. Pelvic examination is normal, and a
Pap smear is done.

Infertility (affected by 15% of couples in United States) is defined as the
inability to achieve pregnancy with frequent and unprotected sexual intercourse
for 12 months if woman age <35 or 6 months if woman age ≥35. Both male
and female factors have to be evaluated in the patient with infertility.


Fecundability is the likelihood of conception occurring with one cycle of
appropriately timed mid-cycle intercourse. With the female partner age 20, the
fecundity rate is 20%. By age 35, the rate drops to 10%.

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