USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

(Kiana) #1

FETAL DEMISE


A   28-year-old multigravida    at  33  weeks’  gestation   comes   to  the office
stating she has not felt her baby move for 24 hours. A previous 18-week
sonogram showed a single fetus with grossly normal anatomy. You are
unable to find fetal heart tones by auscultation with a Doppler stethoscope.

From a medical viewpoint, fetal demise applies to any death after the embryo
period (≥10 menstrual weeks). From a perinatal statistics viewpoint, the term
applies to in utero death of a fetus after 20 weeks’ gestation before birth.


Antenatal demise occurs before labor. Intrapartum demise defines death that
occurs after the onset of labor.


Significance


Fetal demise is most commonly idiopathic. When a cause is identified, risk
factors include antiphospholipid syndrome, overt maternal diabetes, maternal
trauma, severe maternal isoimmunization, fetal aneuploidy, and fetal infection.


Disseminated    intravascular   coagulation (DIC)   is  the most    serious
consequence, with prolonged fetal demise (>2 weeks) resulting from release
of tissue thromboplastin from deteriorating fetal organs.
Grief resolution may be prolonged if psychosocial issues are not appropriately
addressed.
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