Handbook of Herbs and Spices - Volume 3

(sharon) #1

Lemon balm 397


lemon balm may therefore have a potential as a weed control in organic agriculture


systems where only organic substances are allowed. However, for commercial use,


much work should be carried out. Moreover, lemon balm extract also has an insecticidal


activity and causes a significant reduction in the growth of the cotton worm (Spodoptera


littoralis) larvae population (Pavela, 2004).


23.6 Quality issues..................................................................................


Medicinal and aromatic plants such as lemon balm are traditionally harvested from


flora or cultivated field, dried and then stored until required for use. The quality of


lemon balm has traditionally been based on appearance. However, efficacy of the raw


material in many herbs varies, dependent on species and even different parts of the


same species, not to mention cultural applications and harvesting time. In addition,


value-added products, where plant appearance has been destroyed, make impossible


visual assessments for species identification. These processed products can range


from ground-dried raw material to liquid or solid extracts or capsules including a


formulation, sometimes containing more than one herb. As such products cannot be


detected with organoleptic techniques, chromatographic techniques such gas


chromatography or HPLC can be employed for identification. Setting chemical quality


standards has progressed slowly because of a lack of conclusive clinical evidence for


the activity of specific compounds, multiple active constituents, synergistic effects,


and the reluctance of some health authorities to agree on recognition of medicinal


herbs as valid therapeutic agents (Wills et al., 2000). Some standards and specifications


for raw material and essential oil of lemon balm are presented in Table 23.1.


23.7 References.......................................................................................


AKHONDZADEH S, NOROOZIAN M, MOHAMMADI M, OHADINIA S, JAMSHIDI AH and KHANI M (2003), ‘Melissa
officinalis extract in the treatment of patients with mild to moderate Alzheimer’s disease: a
double blind, randomised, placebo controlled trial’, Journal of Neurology Neurosurgery and
Psychiatry, 74(7), 863–866.
ALLAHVERDIYEV A, DURAN N, OZGUVEN M and KOLTAS S (2004), ‘Antiviral activity of the volatile oils of
Melissa officinalis L. against Herpes simplex virus type-2’, Phytomedicine, 11(7–8), 657–661.
ARAUJO C, SOUSA MJ, FERREIRA MF and LEAO C (2003), ‘Activity of essential oils from Mediterranean
Lamiaceae species against food spoilage yeasts’, Journal of Food Protection, 66(4), 625–632.
BOLKENT S, YA NARDAG R, KARABULUT-BULAN O and YESILPARMAK B (2005), ‘Protective role of Melissa
officinalis L. extract on liver of hyperlipidemic rats: A morphological and biochemical study’,
Journal of Ethnopharmacology, 99, 391–398.
BOMBIK T, BOMBIK A and SABA L (2002), ‘Effects of a herb extract on the level of selected biochemical
indicators in the blood of calves’, Medycyna Weterynaryjna, 58(6), 464–466.
BOZAN B (1995), ESOP and therapy with plants in Europe, Anadolu University, Research Centre of
Medicinal and Aromatic Plants, Medicine, TAB Bulletin, 11.
CAPECKA E, MARECZEK A and LEJA M (2005), ‘Antioxidant activity of fresh and dry herbs of some
Lamiaceae species’, Food Chemistry, 93, 223–226.
CARNAT AP, CARNAT A, FRAISSE D and LAMAISON JL (1998), ‘The aromatic and polyphenolic composition
of lemon balm (Melissa officinalis L. subsp. officinalis) tea’, Pharmaceutica Acta Helvetiae, 72,
301–305.
CEYLAN A, BAYRAM E and OZAY N (1994), ‘Investigations on agronomic and technological characteristics
of lemon balm (Melissa officinalis L.)’, Turkish Journal of Agricultural and Forestry, 18,
125–130.

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