478 Handbook of herbs and spices
techniques. Recent data reported that peppermint oil is used at a concentration of
< = 3% in rinse-off formulations and < = 0.2% in leave-on formulations. This
concentration of use data coupled with the < = 1% restriction on pulegone suggested
to the panel that pulegone toxicity would not be seen with cosmetic use. On the basis
of the available data, the CIR Expert Panel concluded that peppermint oil, extract,
leaves, and water are safe as used in cosmetic formulations. The concentration of
pulegone in these ingredients should not exceed 1%.
28.7 References.......................................................................................
AKDOGAN M, OZGUNERB M, KOCAKB A, ONCUB M and CICEKC E. 2004. Effects of peppermint teas on
plasma testosterone, follicle-stimulating hormone, and luteinizing hormone levels and testicular
tissue in rats. Urology, 64 : 394–98.
ANONYMOUS. 2001. Final report on the safety assessment of Mentha piperita (Peppermint) Oil,
Mentha piperita (Peppermint) Leaf extract, Mentha piperita (Peppermint) Leaf, and Mentha
piperita (Peppermint) Leaf water. Int. J. Toxicol., 20 , supplement 3: 61–73.
ANSARI MA, VASUDEVAN P, TANDONB M and RAZDANA RK. 2000. Larvicidal and mosquito repellent action
of peppermint (Mentha piperita) oil. Bioresource Technology, 71 : 267–71.
AREIAS FM, VALENTÃO PB, ANDRADE F, FERRERES^ and SEABRA RM. 2001. Phenolic fingerprint of peppermint
leaves. Food Chemistry, 73 : 307–11.
BASLAS RK. 1970. Studies on the influence of various factors on the essential oil from the plants of
Mentha piperita. Flavour Ind., 1 : 185–87.
BEITZ H, SEEFELD and PANK F. 1971. Residues of plant protection agents on medicinal and flavoring
plants: Lindane residues on fennel and peppermint. Pharmazie, 26 : 644–45.
BHARADWAJ SD, KAUSHAL AN, KATOCH PC and GUPTA R. 1980. Level and time of nitrogen application to
peppermint (Mentha piperita L.) at Solan (HP). Indian Perfum., 24 : 27–30.
BRADLEY P.R. (ed.). 1992. British Herbal Compendium, Vol. 1. Bournemouth: British Herbal Medicine
Association.
BRIGGS CJ. 1973. Effects of polybutene emulsion sprays on the composition of peppermint oils.
Planta Med., 24 : 120–26.
BRIGGS C. 1993. Peppermint: Medicinal Herb and Flavouring Agent. CPJ/RPC 89–92.
British Herbal Pharmacopoeia (BHP). 1996. Exeter, U.K.: British Herbal Medicine Association.
149.
BRUNETON J. 1995. Pharmacognosy, Phytochemistry, Medicinal Plants. Paris: Lavoisier Publishing.
CAPECKA E, MARECZEKB A and LEJAB M. 2004. Antioxidant activity of fresh and dry herbs of some
Lamiaceae species. Food Chem., 93 : 223–26.
CARLING L, SVEDBERG LE and HULTEN S. 1989. Short term treatment of the irritable bowel syndrome:
a placebo-controlled trial of Peppermint oil against hyoscyamine. Opuscula Med., 34 : 55–57.
CHALCHAT JC, MICHET A and PASQUIER B. 1997. Influence of harvesting time on chemical composition
of Mentha piperita L. essential oil. Perfum. Flavor., 22 : 15, 17–21.
CLARK RJ and MENARY. 1980. The effect of irrigation and nitrogen on the yield and composition of
peppermint oil (Mentha piperita L.). Aust. J. Agric. Res., 31 : 489–98.
DEW MJ, EVANS BK and RHODES J. 1984. Peppermint oil for the irritable bowel syndrome: a multicentre
trial. Br. J. Clin. Pract., 38 (11–12): 394, 398.
DIEMERA F, JULLIENA F, FAUREA O, MOJAA S, COLSONA M, MATTHYS-ROCHONB E and CAISSARDA JC. 1998.
High efficiency transformation of peppermint (Mentha ¥ piperita L.) with Agrobacterium
tumefaciens. Plant Sci., 136 : 101–8.
DIEMERA F, JEAN-CLAUDE CAISSARDA, MOJAA S, JEAN-CLAUDE CHALCHATB and JULLIEN F. 2001. Altered
monoterpene composition in transgenic mint following the introduction of 4S-limonene synthase.
Plant Physiol. Biochem., 39 : 603–14.
DIPLOCK TA, CHARLEUX JL, CROZIER-WILLI G, KOK FJ, RICE-EVANS C, ROBERFROID M, STAHL W and VIÑA-RIBES
J. 1998. Functional food science and defense against reactive oxidative species. British J.
Nutrition, 80 : 77–112.
DJOUVINOV D, PAVLOV D, ILCHEV A and ENEV E. 1997. Peppermint (Mentha piperita Huds.) and basil
(Ocimum basilicum L.) etheric oil by-products as roughages for sheep feeding. Animal Feed
Science and Technology, 68 : 287–94.