C
use in pregnancy and lactation is to be avoided. May interfere with MAOI therapy, due to the
documented amino acid constituents. However they list mostly ubiquitous amino acids; does
this mean that we should attach the MAOI warning to all herbs (CAN)? Canadian regulations
do not allow chaparral as a nonmedicinal ingredient for oral use products (Michols, 1995).
NDGA may induce mesenteric lymph node and renal lesions in rats. NDGA, with many reported
biological activities, has LD50 = 4000 mg/kg orl mouse, 5500 mg/kg orl rat, and 830 mg/kg
orl guinea pig. Removed from the generally listed as safe (GRAS) list in 1970 (LRNP, August
1993).CHASTEBERRY (Vitex agnus-castus L.) ++Activities (Chasteberry) — Analgesic (1; BGB); Anaphrodisiac (f; BRU; MAB); Anorectic (f;
PH2); Antiandrogenic (1; MAB); Antibacterial (1; APA; MAB; WOI); Antiinflammatory (1; APA);
Antilactagogue (1; PH2); Antiprolactin (1; MAB; PHR; SHT); Antiseptic (1; MAB; WOI); Can-
didicide (1; APA; MAB); Dopaminergic (1; BGB; MAB; PH2; SHT); Emmenagogue (f; BGB;
BRU; MAB; PH2); Fungicide (1; MAB); Lactagogue (1; APA; BRU; CAN; MAB); Progesterogenic
(1; MAB; SKY; WOI); Sedative (f; BRU; PH2).
Indications (Chasteberry) — Acne (2; BRU; CAN; MAB); Alactea (2; MAB); Amenorrhea (1;
APA; MAB); Anemia (1; PH2); Bacteria (1; APA; MAB; WOI); BPH (1; MAB; PH2); Breast