J
after reviewing the literature, claims to debunk the many authors (including Duke, 1985), cautioning
about abortifacient activity of juniper oil. He speculates that they are clouded by the sabine juniper,
which apparently does have abortifacient activities. He found few references indicating abortifacient
activity for juniper oil, and the references suggested that ethanolic and acetone extracts of juniper
berries have antifertility activity in rats. “It seems inconceivable that the juniper oil could be
responsible for the reproductive toxicity noted above. There is no reason to regard juniper oil as
being hazardous in any way” (Tisserand, R., 1995). New perspectives on EO safety. (pp. 16–35 in
IJA, 1995. Aroma’95 - One body - one mind. July 14th-16th, 1995 Conference Proceedings.
Aromatherapy Publications, P.O. Box 746. Hove, E. Sussex, BN3 3XA England. 157 pages.)
Extracts (Juniper) — EO antiseptic, diuretic, irritant, uterotonic (CAN). Aqueous extract hypogly-
cemic. Extracts at first hypertensive, then hypotensive in rats (25 mg/kg ivn). Extracts abortifacient,
antifertility, antiimplantation. Extracts and lignans potent antiherpetics. Berry extracts antiinflam-
matory (>indomethacin). The oil inhibited rat paw edema 60%, while indomethacin inhibited 45%.
LD50 = 3000 mg/kg ipr mouse, LD50 = >3000 mg/kg orl rat (CAN). Phillipson et al. (1995)
studied antimalarial activity of the important antitumor compound, podophyllotoxin, which occurs
in junipers, mayapples, chervils, and perennial flaxes in the temperate zone, in Hernandia and
Hyptis in the tropics. Podophyllotoxin is active against Plasmodium falciparum (IC50 = 10.3 μg/ml),
slightly more active than the synthetic derivative etoposide (14.8 μg/ml) and much more active
than teniposide (inactive at >500 μg/ml) (Phillipson et al., 1995). This lends even more credence
to my favorite antimalarial tonic, gin and tonic with sweet annie, (which see) with juniper’s
antimalarial podophyllotoxins, tonic’s quinine alkaloids, and sweet annie’s artemisinin, and six
other antiplamodial compounds, artemin, casticin, chrysosphlenetin, chrysosplenol-D, cirsilineol,
and eupatorin, all proven synergisitc with artemisinin.JUREMA (Mimosa hostilis Benth.) +Activities (Jurema) — Astringent (1; CRC); Hallucinogen (1; CRC); Narcotic (1; CRC); Uterotonic
(f; CRC).JUTE (leaves only) (Corchorus olitorius L.) +++Activities (Jute) — Analgesic (f; KAB); Antioxidant (ABS; FNF); Antipyretic (f; KAB); Aperitif
(f; KAB); Astringent (f; KAB); Cardiotonic (1; WBB; WOI; ZUL); Demulcent (f; KAB); Diuretic
(f; KAB; SKJ); Hypocholesterolemic (1; ABS); Hypoglycemic (1; ZUL; WBB); Lactagogue (f;
HHB; WBB); Laxative (f; HHB; WBB); Tonic (f; KAB; SKJ; WBB).
Indications (Jute) — Anorexia (f; KAB); Ascites (f; KAB); Cancer (f; JLH); Chest Ache (f; HHB);
Constipation (f; HHB; WBB); Cystosis (f; KAB; SKJ); Dysuria (f; SKJ); Enterosis (f; WBB); Fever
(f; KAB); Gonorrhea (f; KAB; SKJ); Hemorrhoid (f; KAB); Hepatosis (f; HHB); High Cholesterol
(1; ABS); Kernel (f; JLH); Pain (f; HHB; KAB); Pulmonosis (f; WBB); Swelling (f; JLH); Tumor
(f; KAB); Water Retention (f; KAB; SKJ); Wen (f; JLH).
Contraindications, Interactions, and Side Effects (Jute) — Not covered (AHP; KOM; PH2).
Leaves edible. Large doses (drenches) of 100–500 mg/kg powdered seeds killed pigs, following
symptoms of anorexia, dysentery, and vomiting. So keep seed out of your mallow greens (Austral.
Vet. J. 58(6):264–5).
Extracts (Jute) — Ethanolic extracts of seeds, roots, stems, and leaves were colorimetrically
estimated to contain 4120, 110, 230, and 20 ppm cardiac glycosides, respectively. Chlorogenic
acid, 3,5-dicaffeoylquinic acid, quercetin 3-galactoside, quercetin 3-glucoside, quercetin-3-(6-mal-
onylglucoside), and quercetin 3-(6-malonylgalactoside) reported from the edible foliage (ABS).