L
PH2); Sore (f; MAD); Sore Throat (f; APA; MAD; PH2); Stroke (1; APA); Tinnitus (1; BRU);
Tonsilosis (f; KOM); Toothache (f; KOM; MAD); Trichomoniasis (f; CRC); Tuberculosis (f; MAD);
Uvulosis (f; JLH); Vaginosis (f; CRC; KOM); Vertigo (1; BRU); Water Retention (1; MAD); Weakness
(f; KOM); Worm (f; CRC; WOI); Wound (f; APA).
Dosages (Lesser Periwinkle) — 2–4 g powdered herb (PNC); 200 ml boiling water over 1 tsp
herb, 2–3 cups/day (PH2); 15 g herb/250 ml water for infusion (PH2); macerate 100 g herbs in a
liter of wine, steep 10 days (PH2); 2.5–5 ml liquid herb extract (PNC); 2–5 g fluid extract (MAD).
Contraindications, Interactions, and Side Effects (Lesser Periwinkle) — Class 2d. Contraindicated
in constipation and hypotension (AHP). “Health hazards not known with proper therapeutic dosages”
(PH2). Commission E reports hematological changes (e.g., leucocytopenia, lymphocytopenia, reduced
globulin levels) have been observed in animals (AEH). Little cited as allergic or toxic (CRC). PH2
reports skin flushing and GI disturbances. Overdose may seriously lower blood pressure (PH2). LD50
“drug” 1400 mg/kg ipr mouse (HH2), LD50 “mixed alkaloids” 76 mg/kg ipr mouse (HH2), LD50
“mixed alkaloids” 24 mg/kg ivn mouse (HH2), LD50 “mixed alkaloids” 500 mg/kg orl mouse (HH2).LEVANT COTTON (Gossypium herbaceum L.) +Synonym: Gossypium transvaalense G. Watt.
Species not necessarily distinguishable, activities and indications often lumped; see, e.g., JFM and
CRC entries related to G. hirsutum, MAD entries assigned to G. herbaceum, many JLH entries
assigned to the species.
Activities (Levant Cotton) — Abortifacient (1; CRC; FNF; PH2); Aphrodisiac (f; PH2); Astringent
(f; CRC); Contraceptive (1; CRC; PH2); Cytostat (1; PH2); Diuretic (f; CRC); Emmenagogue (1;
AHP; CRC; PH2); Emollient (f; CRC); Hemostat (f; CRC; MAD); Hypercholesterolemic (1; PH2);
Hypertriglyceridemic (f; PH2); Hypocholesterolemic (f; PH2); Lactagogue (f; CRC); Oxytocic (f;
CRC; PH2); Uterotonic (1; AHP); Vasoconstrictor (f; CRC).
Indications (Levant Cotton) — Adenopathy (f; JLH); Amenorrhea (1; MAD; PH2); Anemia (f;
MAD); Asthma (f; CRC; MAD); Bite (f; PH2); Bleeding (f; CRC; MAD; PH2); Bronchosis (f; CRC);
Burn (f; JLH); Cancer (1; CRC; FNF); Cancer, abdomen (f; JLH); Cancer, breast (f; JLH); Cancer,
colon (f; JLH); Cancer, nose (f; JLH); Cancer, uterus (f; JLH); Childbirth (f; HHB; PH2); Climacteric
(f; PH2); Cold (f; JFM); Constipation (f; PH2); Corn (f; JLH); Cough (f; MAD; PH2); Cramp (f;
JFM); Cystosis (f; PH2); Debility (f; MAD); Diarrhea (f; CRC; PH2); Dysentery (f; CRC; JFM;
PH2); Dyslactea (f; JFM; PH2); Dysmenorrhea (1; MAD; PH2); Dysuria (f; JFM); Earache (f; JFM);
Enterosis (f; JFM); Epilepsy (f; PH2); Fever (f; HHB; JFM; MAD); Fibroid (1; CRC; JLH); Gonorrhea
(f; PH2); Headache (f; CRC; PH2); Hemorrhoid (f; CRC; JFM); High Blood Pressure (f; JFM); High
Cholesterol (f; PH2); Hypochondria (f; CRC); Infertility (f; MAD); Inflammation (f; JFM; PH2);
Laryngosis (f; JFM); Menorrhagia (f; PH2); Metrorrhagia (f; PH2); Morning Sickness (f; MAD;
PH2); Nausea (f; PH2); Neurosis (f; PH2); Pain (f; JFM; PH2); Polyp (f; CRC; FNF); Pulmonosis
(f; JFM; MAD); Rheumatism (f; JFM); Rhinosis (f; JLH); Snakebite (f; PH2); Tumor (1; CRC; FNF);
Urethrosis (f; PH2); Uterosis (f; CRC; FNF); UTI (f; JFM); Wart (f; JLH); Water Retention (f; CRC).
Dosages (Levant Cotton) — 100 g root in 1 liter water, reduced by boiling to 0.5 liter, take 50 g liquid
every half hour (dangerous formula for abortion; CRC); 1–2 tbsp fluid extract during childbirth (HHB);
3 leaves in 1 liter water for hypertension (JFM); 6–8 g seed/150 g water or milk, 3 ×/day as lactagogue
(f; JFM); 1.8–3.75 g root bark, 20–40 drops liquid extract (PH2); 2–4 ml liquid extract (PH2).Contraindications, Interactions, and Side Effects (Levant Cotton) — Class 2b (AHP).
Contraindicated in urogenital irritation or tendency to inflammation; may sterilize men (AHP).
“Hazards and/or side effects not recorded for proper therapeutic dosages” (PH2). Drug toxic