Yet another type of glial cell is the astrocyte(liter-
ally, “star cell”). In the embryo, these cells provide a
framework for the migrating neurons that will form
the brain. Thereafter, the extensions of astrocytes are
wrapped around brain capillaries and contribute to the
blood–brain barrier, which prevents potentially
harmful waste products in the blood from diffusing
out into brain tissue. These waste products are normal
in the blood and tissue fluid, but brain tissue is much
more sensitive to even low levels of them than are
other tissues such as muscle tissue or connective tis-
sue. The capillaries of the brain also contribute to this
barrier, because they are less permeable than are other
capillaries. A disadvantage of the blood–brain barrier
is that some useful medications cannot cross it, and
the antibodies produced by lymphocytes cross only
with difficulty. This becomes an important considera-
tion when treating brain infections or other diseases
The Nervous System 167
Afferent (sensory) neuron
Axon terminal
Axon
Nucleus
Cell body
Functional dendrite
Myelin sheath
Receptors
Dendrites
Nucleus
Axon terminal
Efferent (motor) neuron
Cell body
Axon
Schwann cell nucleus
Myelin sheath
Node of
Ranvier
A B
Schwann cell
Axon
Neurolemma
Layers of myelin sheath
C
Figure 8–1. Neuron struc-
ture. (A) A typical sensory neu-
ron. (B) A typical motor neuron.
The arrows indicate the direc-
tion of impulse transmission.
(C) Details of the myelin sheath
and neurolemma formed by
Schwann cells.
QUESTION:The axon terminal
of the motor neuron would be
found at what kinds of effec-
tors?