and diminished glucose metabolism, 163
and plaque buildup in the brain, 101
reversing, 300
testing for, 103–5, 106
insulin sensitivity
overview, 108
and fasting, 289
gluten vs., 108–9
and IRS-1, 104
restoring or preserving, 60, 114, 115, 131
intermittent fasting, 151–53, 238, 288–91
iodine and iodine deficiency, 295–96
IRS-1 (insulin receptor substrate 1) protein, 104
Isaacson, Richard, 132–33, 163
isocaloric vs. isometabolic, 77
Isokauppila, Tero, 335
Jacka, Felice, 174, 224–25
Jamaican Me Smarter, 324–25
JAMA Neurology (journal), 218
Japanese dietary pattern, 40
John Hopkins University, 222
Journal of the American Medical Association, 19, 30, 297
junk food, 85, 110, 173n, 249, 315
Karolinska Institutet, Stockholm, 18–19
Kenya study, 174–75
ketogenic days on Genius Plan, 315–17, 319
ketogenic diet, 154–57, 165
ketone bodies