C
Neuralgia (f; CRC; FEL; HHB; MPI; PH2); Neurosis (f; CRC; PH2); Pain (1; CRC; FEL; PH2; PNC;
WO2); Palpitation (1; MPG); Pertussis (f; CRC; HHB; MPI); Pinworm (f; CRC; WO2); Pneumonia
(f; FEL; CRC; MPI); Pyemia (f; MPI); Rash (f; PH2); Respirosis (f; PH2); Rheumatism (f; FEL;
MPI); Rhinosis (f; MPI); Sciatica (f; CRC; PH2); Septicemia (f; CRC); Sore (f; JLH; PHR; PH2);
Sore Throat (f; CRC; MPI); Splenomegaly (f; PHR; PH2); Splenosis (f; JLH; MPI); Stomatosis (f;
CRC); Tachycardia (1; 60P); Tonsilosis (1; MPI); Trachoma (f; FEL); Tumor (1; CRC; JFM); Typhoid
(f; CRC; FEL); Ulcer (f; JLH); Varicosis (f; CRC; WO2); Wen (f; JLH); Wound (f; PHR; PH2).
Dosages (Cinchona) — 1 tsp bark boiled 5–10 min, 3 ×/day (MPG); 1–3 g bark (KOM); 10 grains
for hay fever, hemicrania, neuralgia, pertussis, splenomegaly (MPI); 0.3–1 g powdered bark (PNC);
0.3–1 ml liquid extract (PNC); 0.3–1 ml cinchona extract (PNC); 2–4 ml cinchona tincture (PNC);
maximum dose 50 mg alkaloids (PNC).
Contraindications, Interactions, and Side Effects (Cinchona) — Commission E reports contrain-
dications; pregnancy and hypersensitivity; adverse effects: allergic reactions, rarely thrombocytopenia;
and interaction: potentiation of coumarin derivatives. Other sources report contraindication for GI-ulcer,
adverse effects for allergic skin reactions and fever. Overdosing or prolonged use may produce toxic
effects (AEH). 8–20 g quinine may be fatal in humans (WO2).
Extracts (Cinchona) — Cinchonidine, cinchonine, hydroquinine, quinidine, and quinine all oxy-
tocic in experimental animals at levels of 0.5–10 mg/kg (WO2). Cinchonidine, cinchonine, quini-
dine, and quinine are some of the antipyretic compounds in this growing medicine chest called
quinine. From an amebicidal point of view, compounds modified from quinine and quinidine were
not as potent as emetine and derivatives (I might mix my ipecac and quinine in Amazonia). Chloro-
9-desoxy-quinine and quinidine were least active, while 9-desoxy-dihydro derivatives showed fair
activity. More compounds that showed slight in vitro activity were also active in vivo, exceptions
being 9-desoxy-dihydro quinine and quinidine, which were active in vivo (MPI).CINNAMON (Cinnamomum verum J. Presl) +++Synonyms — C. zeylanicum Blume, Laurus cinnamomum L.