H
Asthma (f; IED; KAP); Bacteria (1; KAP; MPI; WBB); Biliousness (f; KAB); Boil (f; KAP; NUT);
Burn (f; JLH; NUT; TRA); Calculus (f; KAB); Cancer (1; JLH; TRA); Cancer, abdomen (f; PH2);
Cancer, colon (f; JLH); Cancer, liver (f; JLH); Cancer, nasopharynx (1; KAP; MPI); Cancer, spleen
(f; JLH); Cardiopathy (f; PH2); Caries (f; SKJ; SUW); Catarrh (f; HHB; KAP; NUT); Cholera (1;
SKJ; WBB); Circulosis (f; SUW); Cold (f; JFM); Colic (f; PH2); Constipation (f; HHB; JFM;
NUT; PH2); Convulsion (f; NUT); Cough (f; JFM; KAP); Cramp (f; HHB; KAP; SUW); Dandruff
(f; PH2); Debility (f; SUW); Dermatosis (f; JFM; PH2); Diabetes (f; PH2); Dropsy (f; IED; KAP;
NUT); Dysentery (f; NUT); Dysmenorrhea (f; SKJ); Dyspepsia (f; KAP; PH2); Dysuria (f; NUT);
Earache (f; IED); Edema (f; JFM; PH2); Enterosis (f; JLH; PH2); Epilepsy (f; IED; PH2; SUW);
Erysipelas (f; NUT); Escherichia (1; TRA; WOI); Fever (f; IED; JFM; PH2; SUW); Fracture (f;
SKJ); Fungus (1; MPI; WBB); Gas (f; KAB; SUW); Gastrosis (f; PH2); Gingivosis (f; KAB); Gout
(f; IED; KAP); Gravel (f; NUT; SKJ); Hallucination (f; KAB); Headache (f; JFM; PH2); Heart (f;
KAB); Hematuria (f; NUT; SKJ); Hepatosis (f; HHB; JLH; SUW); Hiccup (f; KAB); High Blood
Pressure (1; HHB; MPI; WBB); Hoarseness (f; KAB); Hysteria (f; IED; KAB; SUW); Immunode-
pression (1; TRA); Induration (f; JLH); Infection (1; KAP; WBB); Infertility (f; NUT); Inflammation
(1; KAB; KAP; MPI; PH2; TRA); Insomnia (1; HHB); Leprosy (f; KAB); Leukemia (f; KAP;
MPI); Low Blood Pressure (1; HHB; MPI; NUT); Lumbago (f; KAB; PH2); Madness (f; NUT);
Maggot (f; NUT); Malaria (f; JFM; KAP; PH2; SUW); Mycosis (1; HHB; MPI; NUT); Myosis
(f; KAB); Nephrosis (f; JFM); Nervousness (1; HHB); Neuralgia (f; KAB; NUT); Ophthalmia (f;
KAB); Pain (1; JFM; KAB; KAP; MPI; SKJ; SUW; WBB); Palsy (f; KAB; SUW); Pancreatosis
(f; WBB); Paralysis (f; KAB; PH2; SUW); Pharyngosis (f; KAB; KAP); Pneumonia (f; NUT; SKJ);
Rheumatism (1; IED; JFM; KAP; PH2; SUW); Rhinosis (1; KAP); Salmonella (1; TRA; WOI);
Scabies (f; NUT); Scirrhus (f; JLH); Scrofula (f; NUT); Shigella (1; TRA; WOI); Snakebite (f;
IED; PH2); Sore (f; KAB; PH2); Sore Throat (f; KAB); Spasm (f; IED); Splenomegaly (f; PH2);
Splenosis (f; JLH; HHB; PH2; SUW); Staphylococcus (1; MPI; WBB; WOI); Stomatosis (f; KAB);
Stone (f; KAP); Streptococcus (1; WBB); Swelling (1; JFM; KAP; MPI); Syncope (f; KAB; SUW);
Syphilis (f; NUT); Tetanus (f; KAB; SUW); Toothache (f; NUT); Tuberculosis (1; KAP); Tumor
(1; NUT; TRA); Ulcer (f; IED); VD (f; NUT; SUW); Vertigo (f; NUT; PH2); Virus (1; KAP; MPI);
Wart (f; JFM); Water Retention (1; JFM; KAP; NUT); Worm (f; HHB; JFM; KAB; PH2); Wound
(f; IED; PH2); Yellow Fever (f; IED; NUT).
Dosages (Horseradish Tree) — 1 tsp root bark tincture in syrup every 3 hours for malaria and
nephrosis (JFM).
Contraindications, Interactions, and Side Effects (Horseradish Tree) — Not covered (AHP;
KOM). “Hazards and/or side effects not known for proper therapeutic dosages” (PH2). 15 g root
bark is an abortive (HHB), hence contraindicated in pregnancy (PH2). 5 g/kg led to gastric
hyperkeratosis and liver steatosis orally in rat (PH2). Parenteral dose of 22–50 mg/kg glucosinolate
is lethal in mice.
Extracts (Horseradish Tree) — Juice from leaves and stem bark inhibit Staphylococcus aureus
but not Escherichia coli (MPI). Another study showed bark extracts were active against Bacillus
subtilis, Dip. pneumoniae, Escherichia coli, Micrococcus pyogenes, Salmonella typhosa, Shigella
dysenteri, Streptococcus pyogenes, and Vibrio comma. Bark extract is fungicidal to Candida albi-
cans, Helminthosporium sativum, Microsporum gypseum, and Trichophyton mentagrophytes. The
50% ethanolic extract of root bark (devoid of antibacterial activity) was antiviral to the vaccinia
virus but not Ranikhet disease virus, but it did inhibit its replication. Ether leaf extracts were
bacteriostatic to Staphylococcus aureus and S. typhosa. Alcohol extracts may contain an adrenergic
neuron blocking agent (MPI). Alcoholic root bark extract analgesic, antiedemic, and antiinflam-
matory at 500–1000 mg/kg orally in albino rats (MPI). Aqueous and ethanolic leaf extracts are
bactericidal, hypotensive, sedative, and respirastimulant. LD50 of 50% ethanolic plant extract = 8
mg/kg ipr mouse.