M
CRC; DEP; KAB); Osteosis (f; SKJ); Pain (1; DEP; PNC); Parasite (f; KAB); Pertussis (f;
MAD); Phthisis (f; DEP; KAB; MAD; SKJ; SUW); Pulmonosis (1; MAD); Respirosis (1;
KEB; PH2); Rheumatism (f; DEP; KAB; MAD; SKJ; SUW); Snakebite (f; KAB); Spasm (1;
CRC); Stomachache (f; MAD); Stomatosis (f; CRC); Stone (f; MAD); Strangury (f; CRC;
KAB); Swelling (f; DEP; KAB; WO2); Thirst (f; CRC; KAB); Tuberculosis (1; CRC; DEP;
KAB; KAP; PH2; SKJ); Tumor (f; JLH); VD (f; KAB); Virus (1; WO2); Water Retention (f;
DEP; KAP; SKJ); Worm (f; KAB); Wound (f; KAB).
Dosages (Malabar Nut) — 1–20 grains for asthma and bronchosis (DEP); 1–2 g powdered leaf;
2 g powdered leaf (KAP); 8–16 ml leaf juice (KAP); 10–30 g powdered root bark (KAP); 28–56
ml bark decoction (KAP); 0.5–1.5 g dry herb/day or 1–3 ml day fluid extract (1:2) (KEB); 2–4 ml
tincture; 1–2 ml liquid 1:1 extract (PH2; PNC).
Contraindications, Interactions, and Side Effects (Malabar Nut) — Not covered
(AHP).“Hazards and/or side effects not known for proper therapeutic dosages” (PH2). Con-
traindicated in pregnancy except in assisting delivery (KEB). Potency of vasicine may be
accentuated with piperine.
Extracts (Malabar Nut) — Leaves contain the quinazoline alkaloids deoxyvasicine, vasicine,
and vasicinone; the latter two are respiratory stimulants. At high doses vasicine protects against
histamine-induced bronchospasm in guinea pigs. Its autooxidation product, vasicinone, had
bronchodilatory activity in vitro and in vivo, and relaxes the tracheal muscle in vitro. Vasicinone
is more potent than vasicine with antiasthmatic properties comparable to (NOTE: hype liter-
ature often uses the word comparable to mean can be compared to, not necessarily meaning
equal to) disodium cromoglycate. Vasicinone is reportedly synergetic with vasicine on bron-
chodilation and ciliary movements. Their 1:1 mix is more bronchodilatory and antagonized
histamine-induced bronchoconstriction than vasicine alone or theophylline. The cardiodepres-
sant effect activity of vasicine was normalized by vasicinone. Flowers contain the antiasthmatic
quercetin.
MALABAR TAMARIND
(Garcinia cambogia (Gaertn.) Desr.) ++Synonym: Mangostana cambogia Gaertn.
Activities (Malabar Tamarind) — Anorectic (1; FNF); Antilipolytic (1; FNF); Antiobesity (1;
FNF); Antiseptic (f; WOI); ATP-Citrate-Lyase Inhibitor (1; FNF); Hypocholesterolemic (1; FNF);
Hypotriglyceridemic (1; FNF); Laxative (f; WOI).
Indications (Malabar Tamarind) — Constipation (f; WOI); Dyspepsia (f; WOI); High Cholesterol
(1; FNF); High Triglycerides (1; FNF); Obesity (1; FNF); Rheumatism (f; WOI); Stomatosis (f;
WOI).
Dosages (Malabar Tamarind) — 1500 mg HCA/day (JAMA); 1320 mg HCA in 3 doses/day
(JAMA); 500 mg plant extract 3 ×/day (JAMA); 500 mg plant extract + 100 μg nickel chromium
3 ×/day (JAMA); 800 mg plant extract + 50 mg caffeine + 40 μg chromium picolinate 3 ×/day
(JAMA); 1500 mg plant extract +1200 mg l-carnitine + 600 μg chromium picolinate/day
(JAMA).
Extracts (Malabar Tamarind) — It’s a special type of hydroxycitric acid (HCA) that leads
some promoters (and optimistic scientists they might have hired) to believe, and JAMA to
disbelieve, that this is a good slimming agent. HCAs occur in several fruits; e.g., the mangosteen
and tamarind.