P
Contraindications, Interactions, and Side Effects (Patchouli) — Class 1 (AHP). “Hazards and/or
side effects not known for proper therapeutic dosages” (PH2) (but PH2 designates no specific
quantified dosage! JAD).
PAU D’ARCO (Tabebuia spp.) +Activities (Pau d’Arco) — Abortifacient (1; MAB); Alexeteric (f; CRC); Analgesic (1; CRC;
MAB); Antiaggregant (1; MAB); Antibacterial (1; APA; MAB); Antidote (f; CRC); Antiedemic (1;
MAB); Antiestrogenic (1; MAB); Antiinflammatory (1; MAB); Antilymphosarcomic (1; MAB);
Antimelanomic (1; MAB); Antimetastatic (1; MAB); Antipyretic (f; PED); Antiretroviral (1; MAB);
Antirheumatic (f; MAB); Antiseptic (1; MAB); Antitrypanosomic (1; MAB); Antitumor (1; MAB;
PED); Antiulcerogenic (1; MAB); Antiviral (1; MAB); Aphrodisiac (f; CRC); Astringent (f; PED);
Candidicide (1; MAB); Cytotoxic (1; MAB); Depurative (f; MAB); Digestive (f; APA); Diuretic
(f; CRC; PED); Estrogenic (1; MAB); Fungicide (1; APA; CRC; MAB; PED); Hypoglycemic (f;
APA); Immunodepressant (1; MAB); Immunostimulant (1; MAB); Parasiticide (1; APA; MAB);
Protisticide (1; MAB); Termitifuge (1; CRC).
Indications (Pau d’Arco) — Adenopathy (f; CRC; JLH); Anemia (f; MAB); Athlete’s Foot (1;
APA); Bacteria (1; APA; MAB); Boil (f; CRC); Cancer (1; APA; MAB; PED); Cancer, breast
(1; CRC; FNF; JLH); Cancer, colon (1; CRC; FNF; JLH); Cancer, esophagus (1; CRC; FNF;
JLH); Cancer, intestine (1; CRC; FNF; JLH); Cancer, liver (1; CRC; FNF; JLH); Cancer, lung
(1; CRC; FNF; JLH); Cancer, pancreas (1; CRC; FNF; JLH); Cancer, prostate (1; CRC; FNF;
JLH); Cancer, skin (1; MAB; PED); Cancer, throat (1; CRC; FNF; JLH); Cancer, tongue (1;
CRC; FNF; JLH); Candida (1; MAB); Carcinoma (1; MAB); Chlorosis (f; CRC); Cold (f; CRC);
Dermatosis (1; MAB; PED); Diarrhea (f; CRC); Dysentery (f; CRC; MAB); EBV (1; MAB);
Dysuria (f; CRC); Eczema (1; MAB; PED); Enterosis (f; JLH); Enuresis (f; CRC); Fever (f;
CRC; PED); Fungus (1; APA; CRC; MAB; PED; SKY); Gonorrhea (f; CRC); Headache (f;
CRC); Hemorrhoid (f; PED); Hodgkin’s Disease (f; APA; CRC); Hyperglycemia (f; APA);
Immune Dysfunction (f; SKY); Immunodepression (1; MAB); Incontinence (f; CRC); Infection
(1; APA; CRC; MAB; PED); Inflammation (1; MAB); Leukemia (1; APA; MAB; PED); Lupus
(f; CRC); Malaria (1; MAB); Melanoma (1; MAB); Metastasis (f; JLH); Mycosis (1; APA; CRC;
MAB; PED); Pain (1; CRC; MAB); Parasite (1; APA; MAB); Pharyngosis (f; CRC); Polyp (f;
JLH); Psoriasis (f; PED); Rabies (f; CRC); Rheumatism (f; PED; MAB); Scabies (f; MAB);
Schistosomiasis (1; MAB); Snakebite (f; CRC); Sore Throat (f; MAB); Swelling (1; MAB);
Syphilis (f; CRC); Toothache (f; CRC); Tumor (1; MAB; PED); Ulcer (1; MAB; PED); Vaginosis
(1; MAB); VD (f; CRC); Virus (1; MAB); Wound (1; MAB); Yeast (1; CRC; MAB; SKY).
Dosages (Pau d’Arco) — 15–20 g bark/pint water/day (APA); 1.5–3.5 g dry bark/day (MAB);
15–20 g inner bark/pint/day; 0.25–0.5 cup fresh inner bark (PED); 6–12 g dry inner bark (PED);
9 g dry inner bark:45 ml alcohol/45 ml water (PED); 300 mg bark capsules 3 ×/day (SKY); 3 (505
mg) capsules 3 ×/day (NH); 3–7 ml extract in 45% ethanol (1:2)/day (MAB).
Contraindications, Interactions, and Side Effects (Pau d’Arco) — Class 1 (AHP). Side effects
may include GI distress and nausea. “Whole bark has no known serious side effects” (SKY). Pregnant
and lactating women should avoid (SKY). Guiraud et al. (1994) note that lapachol and beta-lapachone,
though active against Candida, could be harmful. Multiple doses of oral lapachol at 500 mg/kg caused
death with severe histopathological changes. In clinical trials, oral lapachol induced anticoagulant
effects, nausea, and vomiting. After 6 doses at 9 mg/kg, beta-lapachone caused death, following
anorexia, diarrhea, and weight loss (LRNP, July 1990). Napthaquinones (lapachol and beta-lapachone)
have antifungal properties comparable to ketoconazole (SKY). Beta-lapachone is a better antifungal
than ketoconazole (MAB). Since anticancer levels of naphthoquinones are toxic, pau d’arco cannot
currently be recommended as a treatment for cancer (SKY). In large doses, lapachol and other