CutaneousMycoses................................................ 372

Dermatophytes(Dermatomycosesor

Dermatophytoses)..................................... 372

OtherCutaneousMycoses............................. 374

IV Virology

7

GeneralVirology 376

K.A.Bienz

Definition.......................................................... 376

MorphologyandStructure......................................... 377

Classification....................................................... 380

Replication......................................................... 381

ViralProteinSynthesis............................................. 387

Genetics............................................................ 389

Host-CellReactions................................................ 392

CellDestruction(CytocidalInfection,Necrosis).......... 392

VirusReplicationwithoutCellDestruction

(NoncytocidalInfection)................................... 393

LatentInfection............................................ 394

TumorTransformation.................................... 394

CarcinogenicRetroviruses(“Oncoviruses”)........... 394

DNATumorViruses................................... 396

Pathogenesis....................................................... 396

DefenseMechanisms............................................... 399

NonspecificImmuneDefenses............................ 400

SpecificImmuneDefenses................................ 401

Prevention......................................................... 402

Chemotherapy..................................................... 404

LaboratoryDiagnosis.............................................. 405

VirusIsolationbyCulturing............................... 406

DirectVirusDetection..................................... 408

VirusDetectionFollowingBiochemical

Amplification.......................................... 409

Serodiagnosis.............................................. 411

XXII Contents

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Kayser, Medical Microbiology © 2005 Thieme

All rights reserved. Usage subject to terms and conditions of license.