GeneralEpidemiology 25
nizationresistance.Ontheotherhand,apotentiallyharmfuleffectofthe
normalfloraisthattheycanalsocauseinfectionsinimmunocompromised
individuals.
GeneralEpidemiology
&Withinthecontextofmedicalmicrobiology,epidemiologyisthestudyof
theoccurrence,causality,andpreventionofinfectiousdiseasesinthepopu-
lace.Infectiousdiseasesoccureithersporadically,inepidemicsorpandemics,
Table 1. 7 NormalMicrobialFlorainHumans
Microorganisms Microbiotopes
Skin Oral
cavity
Intes-
tine
Upperre-
spiratory
tract
Genital
tract
Staphylococci +++ + + ++ ++
Enterococci ++ +
a-hemolyticstreptococci + +++ + + +
Anaerobiccocci + + +
Pneumococci + +
Apathogenicneisseriae + + +
Apathogeniccorynebacteria ++ + + + +
Aerobicspore-formingbacteria (+)
Clostridia +++ (+)
Actinomycetes +++ +
Enterobacteriaceae (+) (+) +++ (+) +
Pseudomonas +
Haemophilus + ++ (+)
Gram-neg.anaerobes +++ +++ +++ +++
Spirochetes ++ + (+)
Mycoplasmas ++ + + ++
Fungi(yeast) ++ + + + +
Entamoeba,Giardia,Trichomonas + +
+++=numerous,++=frequent,+=moderatelyfrequent,(+)=occasionaloccurrence
1
Kayser, Medical Microbiology © 2005 Thieme