Biology Questions and Answers

(Greg DeLong) #1

Biology Questions and Answers



  1. Is it expected that a
    change in the primary, in the
    secondary or in the tertiary
    structure of a protein will
    produce more functional
    consequences?


Any change of the protein structure is
relevant iChanges in f it alters its biological activity.the primary protein
structure are more important because


they are modificationscomposition of the molecul in thee and such (^)
composition destructures of the protein.termines all other



  1. In sickle cell anemia, a
    hereditary disease, there is
    substitution of one amino acid
    by another in one of the four
    polypeptide chains of
    hemoglobin. In this case are
    all of the structural levels of
    the protein modified?


In sickle cell disease tin the primary protein structure ohere is a chanf onege (^)
of the polypeptide chains that form
hemoglobin: the amino acid is substituted by the amino acid glutamicacid
valine in the β chain. The spatial
conformation is also affected of the molecule and modified by thisin addition
primary “mistake” and the modification
also creatthe red blood cells.es a different (sickle) shape to
Modified, sickled, resometimes aggregate and blood cellsd obstruct (^) the
peripheral circulationhypoxia and the pain crisis causing tissue typical of (^)
sickle cell anemia.



  1. What is the difference
    between essential and natural
    amino acids?
    Essential amino acids arorganism is not able to synthe those esize anthat thed


that need to be ingested by theindividual. Natural amino acids ar (^) e
those that are produced by the
organism.
There are living species that produce
every amiexample, no acid tthe bacteria Eschhey need, forerichia (^) coli,
that does not have essential aminoacids. Other species, like humans, need (^)
to obtain essential amino acids from the
diet. Amoamino acids that fong the twenty different knownrm proteins humans
can make twelve of them and the
remaininthe proteins thg eight need to be taken fromey ingest with food.
The essential amino are phenylalanine, histidine, acids for humansisoleucine, (^)
lysine, methionine, threonine,
tryptophane and valine.



  1. What are respectively
    some remarkable functions of
    myosin, CD4, albumin, keratin,
    immunoglobulin, reverse
    transcriptase, hemoglobin and
    insulin?
    Myosin is a protein that when associated


with actin pcontraction.roduces a m CD4 is a membrane proteinuscular (^)
of some lymphocytes, the cells that are
infected by HIV. Albumistorage protein and also an n is an importantenergy
regulator of the blood osmolarity.
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