Introduction to Human Nutrition

6 Nutrition and Metabolism of Lipids Bruce A Griffi n and Stephen C Cunnane Key messages Lipids are organic compounds composed ...

Nutrition and Metabolism of Lipids 87 In 1929, Mildred and George Burr discovered that the absence of fat in a diet otherwise be ...

88 Introduction to Human Nutrition Lengthening of the chain and the introduction of additional double bonds beyond the fi rst on ...

Nutrition and Metabolism of Lipids 89 Long-chain saturated and monounsaturated fatty acids Long-chain fatty acids (>14 carbon ...

90 Introduction to Human Nutrition Hydrogenated and conjugated fatty acid isomers The introduction of unsaturation with one doub ...

Nutrition and Metabolism of Lipids 91 occupied by more unsaturated fatty acids. At inter- faces between non-miscible polar and n ...

92 Introduction to Human Nutrition skeletal muscle, etc.) of lean, undomesticated animals. By contrast, in domesticated animals, ...

Nutrition and Metabolism of Lipids 93 secreted by the palate, although its contribution to lipolysis in adults is questionable a ...

94 Introduction to Human Nutrition micelles increases the solubility of fat by 100- to 1000- fold. They create an acidic microen ...

Nutrition and Metabolism of Lipids 95 Enterohepatic circulation The absorption of fat in the small intestine is depen- dent on t ...

96 Introduction to Human Nutrition Re-esterifi cation of triacylglycerols in the enterocyte Once LCFAs have entered the cell the ...

Nutrition and Metabolism of Lipids 97 In the small intestine, the newly re-esterifi ed TAGs and CEs associate with specifi c amp ...

98 Introduction to Human Nutrition lipolyzed by a rate-limiting lipase known as lipopro- tein lipase (LPL). LPL is tethered to t ...

Nutrition and Metabolism of Lipids 99 Lipoprotein structure: a shopping bag and groceries The general structure of a lipoprotein ...

100 Introduction to Human Nutrition that, although the liver has the capacity to synthesize fatty acids, the amount synthesized ...

Nutrition and Metabolism of Lipids 101 disease, the most prolifi c of which was the discovery of the LDL receptor pathway by the ...

102 Introduction to Human Nutrition and CHD risk in prospective cohort studies. The activity of the HDL pathway is infl uenced b ...

Nutrition and Metabolism of Lipids 103 of its size, has a much greater potential to infi ltrate the artery wall and deposit its ...

104 Introduction to Human Nutrition potentially harmful cholesterol-rich remnants and LDLs that contribute to coronary atheroscl ...

Nutrition and Metabolism of Lipids 105 Plasma and milk lipids In a way, plasma and milk lipids are an exception to the general r ...