Digestion and Metabolism of Carbohydrates 85
topical application via toothpastes and mouth rinses
prevents dental caries. Too much fl uoride in drinking
water can cause fl uorosis, which damages the skeleton
and teeth. The optimum concentration of fl uoride
in temperate areas of the world is 1 mg/l, falling to
0.6 mg/l in tropical climates where fl uid intake is
likely to be greater.
5.6 Perspectives on the future
The carbohydrate structure and amounts in many
foods and ingredients can be manipulated to achieve
specifi c physicochemical properties of benefi t for
food structure and organoleptic effects and to produce
a diverse range of physiological effects. It can be
expected that many functional foods of the future will
contain such specially selected or modifi ed carbohy-
drates, but the metabolic and health consequences of
these carbohydrates should be examined in more
detail before health claims can be justifi ed.
Future research on carbohydrate nutrition should
also focus on the physiological and biochemical (met-
abolic) effects of the SCFAs produced from nonglyce-
mic carbohydrates.
To provide a sound evidence base for recommen-
dations for intakes of specifi c carbohydrates, the
relationships between intakes of different types and
quantities of carbohydrate with health and disease,
for example during transition of traditional people
and consequent lowering of intakes, should be a fruit-
ful area for research.
References
Burkitt DP, Trowell HC. Refi ned Carbohydrate Foods and Disease.
Academic Press, London, 1975.
Englyst KN, Englyst HN, Hudson GL et al. Rapidly available glucose
in foods: an in vitro measurement that refl ects the glycemic
response. Amer J Clin Nutr 1999; 69 : 448–454.
Englyst HN, Kingman SM, Hudson GJ et al. Measurement of resist-
ant starch in vitro and in vivo. Br J Nutr 1996; 75 : 749–755.
Food and Agriculture Organization of the United Nations. FAO
food and nutrition paper 66. Carbohydrates in human nutrition.
Report of an FAO/WHO Expert Consultation on Carbohydrates,
14–18 April, 1997, Rome, Italy. FAO, Rome, 1998.
Holland B, Unwin ID, Buss DH. Vegetable Dishes. Second supple-
ment to McCance and Widdowson’s The Composition of Foods,
5th edn. Cambridge: Royal Society of Chemistry, 1992.
Jenkins DJA, Wolever TMS, Taylor RH et al. Glycemic index of
foods: a physiological basis for carbohydrate exchange. Am J
Clin Nutr 1981; 34 :362–366.
Mccance RA, Lawrence RD. The carbohydrate content of foods.
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Further reading
Asp N-G. Development of dietary fi bre methodology. In: McCleary
BV, Prosky L, eds. Advanced Dietary Fibre Technology. Blackwell
Science, Oxford, 2001: 77–88.
Brody T. Nutritional Biochemistry, 2nd edn. Academic Press, San
Diego, CA, 1999.
Daly ME, Vale C, Walker M et al. Acute fuel selection in response
to high-sucrose and high-starch meals in healthy men. Am J Clin
Nutr 2000; 71 : 1516–1524.
Johnson LR. Gastrointestinal Physiology, 5th edn. Mosby, St Louis,
MO, 1997.
Rugg-Gunn AJ. Nutrition and Dental Health. Oxford University
Press, Oxford, 1993.
Wolever TMS. The Glycaemic Index: A Physiological Classifi cation
of Dietary Carbohydrate. CABI, Wallingford, 2006.