Resources
BOOKS
Kushner, Robert and Nancy Kushner.Dr. Kushner’s Per-
sonality Type Diet.New York: St. Martin’s Press, 2003.
Kushner, Robert.Evaluation and Management of Obesity.
Daniel Bessesen ed.Philadelphia: Hanley and Belfus,
2002.
Kushner, Robert and Marty Becker.Fitness Unleashed!: A
dog and owner’s guide to losing weight and gaining health
together.New York: Three Rivers Press, 2006.
Kushner, Robert and Daniel Bessesen eds.Treatment of the
Obese Patient.Totowa, NJ: Humana Press, 2007.
Shannon, Joyce Brennfleck ed.Diet and Nutrition Source-
book.Detriot, MI: Omnigraphics, 2006.
Willis, Alicia P. ed.Diet Therapy Research Trends.New
York: Nova Science, 2007.
ORGANIZATIONS
American Dietetic Association. 120 South Riverside Plaza,
Suite 2000, Chicago, Illinois 60606-6995. Telephone:
(800) 877-1600. Website:http://www.eatright.org
OTHER
Kushner, Robert. ‘‘Dr. Kushner’s Personality Type Diet.’’
drkushner.com2007.http://www.doctorkushner
.com(March 22, 2007).
Helen M. Davidson
Phytonutrients
Definition
Phytonutrients are a class of nutrients that are
thought to have health-protecting properties. The pre-
fixphytois from the Greek and means plant, and it is
used because phytonutrients are obtained only from
plants.
Purpose
Unlike the macronutrients (proteins,carbohy-
drates,fats) and micronutrients (vitamins, tracemin-
erals) that are needed for growth,metabolism, and
other body functions, phytonutrients are not consid-
ered essential. This is because they can be lacking in
the diet without harmful health consequences. How-
ever, throughout history, plants have been cultivated
and used to prevent and treat various human diseases.
More recently, understanding the chemical role played
by these phytonutrients in plants has provided new
clues as to how they may help humans. When eating
plant-based foods, some of these phytonutrients iden-
tified as protectors in plants are transferred to our
bodies. The herbs and spices used for adding flavors
and tastes to foods are now known to be associated
with a long list of potential beneficial effects on human
health. Phytochemicals derived from the plants to this
day remain the basis of several medications used for
the treatment of a wide range of diseases. Throughout
the world, botanists and chemists actively search the
plant kingdom for new phytochemicals. Over 40% of
medicines now prescribed in the Unites States contain
chemicals derived from plants. For example, ephe-
drine, a phytochemical, is used in the commercial
preparation of pharmaceutical drugs prescribed for
the relief of asthma symptoms and other respiratory
problems. Phytochemicals isolated from plants have
also been a great help for discovering a large propor-
tion of the drugs now available for the treatment of a
wide range of human diseases such as pulmonary dis-
eases, cardiovascular diseases, diabetes,obesity, and
cancers.
Description
There are three broad classes of phytonutrients:
phytochemicals, medicinal plants and herbs and spices.
Phytochemicals
Thousands of phytochemicals have been isolated
and characterized from plants, including fruits and
vegetables. The most well-known include include ter-
penes,carotenoids, flavonoids, limonoids, and phy-
tosterols. In nature the bright green and red pigments
present in cabbages and lettuce, tomatoes and straw-
berries have evolved to help absorb otherwise harmful
ultraviolet radiation from the sun. They include the
yellow, orange, and red carotenoids. Green and leafy
SOURCE: Agricultural Research Service, U.S. Department of
Agriculture
Ways phytonutrients may protect human health
Serve as antioxidants
Enhance immune response
Enhance cell-to-cell communication
Alter estrogen metabolism
Convert to Vitamin A (beta-carotene is metabolized to vitamin A)
Cause cancer cells to die (apoptosis)
Repair DNA damage caused by smoking and other toxic exposures
Detoxify carcinogens through the activation of the cytocrome P450 and
Phase II enzyme systems
More research is needed to firmly establish the mechanisms of action of the
various phytochemicals
(Illustration by GGS Information Services/Thomson Gale.)
Phytonutrients