cybernetics, 183
Dalai Lama, 41
dangers of psychedelics, 14 –15, 209 –11, 209n
Davis, Wade, 107 , 274
death and dying
death rehearsal process, 346 , 389
deaths associated with psychedelics, 14 , 211
fear of, 8 , 78 –79, 218 , 223 , 336 –37, 339 , 346 –47, 353 , 355 , 404
Griffiths’s outlook on, 79 –80
and hospice services, 401
near-death experiences, 306
perceptions of, 68 , 70 , 79
and Pollan’s psychedelic journeys, 267 , 269
reconnections with the dead, 67
visions of, 345 –46
See also cancer patient research
default mode network (DMN)
activity reductions in, 300 , 304 –6, 313 –14, 316 –20, 322
and autobiographical narratives, 304 , 387 –88, 391
and children’s brains, 312 , 328
and depression, 313 , 378 , 387 –88
discovery of, 301 –2
and disorganizing effect of psychedelics, 314n
effect of psilocybin on, 300 –301, 304 –5
and ego, 312 , 313 –14, 329 , 387 , 388
and ego dissolution, 304 –5, 351
evolution of, 312
and existential distress, 353
and expansion/contraction of consciousness, 322 –23
function of, 301 –4, 306 –7
key structures of, 301n
and mental illness, 329 , 386
and mental time travel, 387
and mystical experiences, 306
overactivity in, 313 , 353 , 378 , 386
and posterior cingulate cortex, 387 –88, 391 –93
quieting through meditation, 305 , 306 , 391 , 392 –95
and relationship to nature, 315 –16
and rewiring of brain, 316 –20, 353 –54
and snow trails metaphor, 385
Delysid (LSD-25), 142 –43, 145 –46, 216 –17
depatterning factor, 124
depression, 375 –81
and access to emotions, 379 –80
addiction’s links to, 383
and antidepressants, 147 , 293 , 335 , 335n, 382
and autobiographical narratives, 387 –88
Carhart-Harris’s pilot study on, 329 –30, 376 –81