How to Change Your Mind

(Frankie) #1
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substances such as peyote and sacred mushrooms) has
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Not long after, Bill Richards and Mary Cosimano, a social worker and
school guidance counselor Richards recruited to help him guide
psychedelic sessions, administered the first legal dose of psilocybin to an
American in twenty-two years. In the years since, the Hopkins team has
conducted more than three hundred psilocybin sessions, working in a
variety of populations, including healthy normals, long-term and novice
meditators, cancer patients, smokers seeking to break their habit, and
religious professionals. I was curious to get the volunteer’s-eye view of
the experience from all these types, but especially from that first cohort of
healthy normals, partly because they were participants in a study that
would turn out to be historically important and partly because I figured
they would be the most like, well, me. What is it like to have a legally
sanctioned, professionally guided, optimally comfortable high-dose
psilocybin experience?
Yet the volunteers in the first experiments were not exactly like me,
because at the time I doubt I would have read past “Interested in the
Spiritual Life?” There were no stone-cold atheists in the original group,
and interviews with nearly a dozen of them suggested many if not most of
them came into the study with spiritual leanings to one degree or
another. There was an energy healer, a man who’d done the whole Iron
John trip, a former Franciscan friar, and an herbalist. There was also a
physicist with an interest in Zen and a philosophy professor with an
interest in theology. Roland Griffiths acknowledged, “We were interested
in a spiritual effect and were biasing the condition initially [in that
direction].”
That said, Griffiths went to great lengths in the design of the study to
control for “expectancy effects.” In part this owed to Griffiths’s skepticism
that a drug could occasion the same kind of mystical experience he had
had in his meditation: “This is all truth to Bill and hypothesis to me. So

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