Ganong's Review of Medical Physiology, 23rd Edition

(Chris Devlin) #1
CHAPTER 30Origin of the Heartbeat & the Electrical Activity of the Heart 505

the QRS complex (ventricular depolarization), and the T wave
(ventricular hyperpolarization). Various arrhythmias can be de-
tected in irregular ECG recordings.
■ Because of the contribution of ionic movement to cardiac mus-
cle contraction, heart tissue is sensitive to ionic composition of
the blood. Most serious are increases in [K+] that can produce
severe cardiac abnormalities, including paralysis of the atria and
ventricular arrhythmias.

MULTIPLE-CHOICE QUESTIONS


For all questions, select the single best answer unless otherwise directed.



  1. Which part of the ECG (eg, Figure 30–5) corresponds to ventric-
    ular repolarization?
    A) the P wave
    B) the QRS duration
    C) the T wave
    D) the U wave
    E) the PR interval

  2. Which of the following normally has a slowly depolarizing
    “prepotential”?
    A) sinoatrial node
    B) atrial muscle cells
    C) bundle of His
    D) Purkinje fibers
    E) ventricular muscle cells

  3. In second-degree heart block
    A) the ventricular rate is lower than the atrial rate.
    B) the ventricular ECG complexes are distorted.
    C) there is a high incidence of ventricular tachycardia.
    D) stroke volume is decreased.
    E) cardiac output is increased.
    4. Currents caused by opening of which of the following channels
    contribute to the repolarization phase of the action potential of
    ventricular muscle fibers?
    A) Na+ channels
    B) Cl– channels
    C) Ca2+ channels
    D) K+ channels
    E) HCO 3 – channels
    5. In complete heart block
    A) fainting may occur because the atria are unable to pump
    blood into the ventricles.
    B) ventricular fibrillation is common.
    C) the atrial rate is lower than the ventricular rate.
    D) fainting may occur because of prolonged periods during
    which the ventricles fail to contract.


CHAPTER RESOURCES
Hile B: Ionic Channels of Excitable Membranes, 3rd ed. Sinauer
Associates, Inc., 2001.
Jackson WF: Ion channels and vascular tone. Hypertension
2000;35:173.
Jessup M, Brozena S: Heart failure. N Engl J Med 2003;348:2007.
Morady F: Radiofrequency ablation as treatment for cardiac
arrhythmias. N Engl J Med 1999;340:534.
Nabel EG: Genomic medicine: cardiovascular disease. N Engl J Med
2003;349:60.
Roder DM: Drug-induced prolongation of the Q-T interval. N Engl J
Med 2004;350:1013.
Rowell LB: Human Cardiovascular Control. Oxford University Press,
1993.
Wagner GS: Marriott’s Practical Electrocardiography, 10th ed.
Lippincott Williams and Wilkins, 2000.
Free download pdf