■ BP and coronary perfusion pressure
■ Will HR and myocardial O 2 demand
■ Intra-aortic balloon pump as bridge to revascularization or valvular repair
(contraindicated in acute aortic regurgitation)
■ Treat any precipitating events
■ Blood pressure control
■ Correct dysrhythmias (rate control or conversion)
■ Treat infection, ischemia, etc.
■ Avoid
■ Nitrates in patients taking erectile dysfunction drugs.
■ Nitrates in severe aortic stenosis, RV infarct, and diastolic dysfunction
(need preload!)
■ Excessive diuresis in patients with acute pulmonary edema or preload
dependent states (may actually need the intravascular volume)
Table 2.11 summarizes the medications for decompensated heart failure and
pulmonary edema.
COMPLICATIONS
■ Dysrhythmias and sudden death
■ Intracardiac thrombus and embolism
■ Progression of disease
Stable Chronic Heart Failure
SYMPTOMS
■ The New York Heart Association (NYHA) classifies heart failure based on
severity of symptoms (see Table 2.12). These classifications have prognostic
and treatment implications.
→
CARDIOVASCULAR EMERGENCIES
TABLE 2.11. Medications for Decompensated Heart Failure and Pulmonary Edema
MEDICATION BENEFICIALEFFECTS DELETERIOUSEFFECTS
Nitroglycerin ↓Preload Severe hypotension with:
↓Afterload (high doses) Viagra use
Coronary vasodilation Aortic stenosis
Hypertrophic cardiomyopathy
RV infarct
Morphine ↓Catecholamines CNS and respiratory depression
↓Preload (mild)
↓Anxiety, pain
Furosemide Immediate venodilator Hypotension from hypovolemia
effect (↓preload) Hypokalemia
Delayed diuresis
Nitroprusside ↓Afterload Coronary steal
↓Preload Hypotension
Coronary vasodilation
Nesiritide Diuresis Hypotension
↓Preload Renal failure
↓Afterload ?Increased mortality