The most common predisposing risk factor (see Table 2.19) for aortic dissection =
uncontrolled HTN.
PATHOPHYSIOLOGY
■ Disruption of intima of aortic wall →blood travels (dissects) into media,
creating false lumen.
■ Dissection can propagate down/up the aorta through the false lumen:
■ Proximally into aortic root →right coronary artery involvement, tam-
ponade, aortic regurgitation
■ Into carotid artery →stroke symptoms
CARDIOVASCULAR EMERGENCIES
Proximal dissection Distal dissection Proximal & distal
dissection
DeBakey II
Stanford A
DeBakey III
Stanford B
DeBakey I
Stanford A
DeBakey
IIIa
DeBakey
IIIb
FIGURE 2.17. DeBakey and Stanford classifications of aortic dissection.
(Reproduced, with permission, from Brunicardi FC. Schwartz’s Principles of Surgery, 8th ed,
New York: McGraw-Hill 2005:704.)
TABLE 2.19. Risk Factors for Aortic Dissection
Uncontrolled hypertension
Advancing age
Connective tissue disease
(eg, Marfan syndrome)
Congenital heart disease
(eg, bicuspid aortic valve)
Giant cell arteritis
Annuloaortic ectasia
Family history
Stimulant abuse
Iatrogenic
(catheterization or surgery)