ORTHOPEDICS
DIFFERENTIAL
Septic hip, psoas abscess, sciatic, herniated disc, pyelonephritis, ankylosing
spondylitis
DIAGNOSIS
■ X-rays show symmetric erosion and sclerosis of the SI joint.
■ MRI of SI joint
■ Aspiration and blood cultures if infection suspected
TREATMENT
Depends on underlying cause (eg, anti-inflammatory agents for inflammatory
causes, antibiotics if infection suspected)
COMPLICATIONS
May be a part of a larger inflammatory arthritis, ie, ankylosing spondylitis,
which is a seronegative spondyloarthropathy typically found in young males
with prolonged (>3 months) back pain
RHABDOMYOLYSIS
Breakdown of muscle that leads to a cascade of events, including: hypo-
volemia (fluid build-up in injured myocytes); hyperkalemia (from release of the
intracellular stores in the injured myocytes); and renal failure (from clogging of
glomeruli with myoglobin and toxic effects of myocyte breakdown products);
accounts for about 10% of all cases of acute renal failure
SYMPTOMS/EXAM
■ Symptoms are often very subtle; must maintain a high index of suspicion.
■ Only half of patients complain of muscle pain.
■ Only a small fraction of patients complain of dark urine.
■ Tender or focal muscle swelling is rare. If present, must consider compart-
ment syndrome!
ETIOLOGY
■ Trauma (most common)
■ Ischemia
■ Polymyositis
■ Toxins/drugs
■ Excessive muscle activity
■ Seizures
■ Burns
■ Sepsis
■ Viral illness
DIAGNOSIS
■ CK>5–10x above normal. However, if CK levels >2–3x normal, repeat
CK level—it peaks about 24 hours from initial insult.
■ Urine dipstick test is positive for blood (globin) but there are no RBCs
in the urine microscopic exam.
■ LDH and AST are elevated.
■ Check serum for elevated potassium, phosphate, creatinine. Serum calcium
may be low.