THORACIC AND RESPIRATORYDISORDERSSPONTANEOUS AND IATROGENIC PNEUMOTHORAXPneumothorax is defined as the presence of air in the pleural space.
■ Spontaneous pneumothorax:Not caused by any obvious external factor
(eg, trauma)
■ 1 °spontaneous pneumothorax: No clinically apparent lung disease;
usually tall, thin males
■ 2 °spontaneous pneumothorax:Occurring in patients with underlying
pulmonary disease process (see Table 10.18)
■ Iatrogenic pneumothorax: The result of diagnostic (thoracentesis) or ther-
apeutic intervention (central venous catheter placement)
SYMPTOMS/EXAM
■ Most patients present with unilateral chest pain (either sharp or steady
pressure) and acute shortness of breath.
■ Patients with significant underlying lung disease may present with signifi-
cant distress, even with a small pneumothorax.
TABLE 10.17. Exudative Pleural Fluid Analysis and Interpretation
PLEURALFLUIDTEST INTERPRETATIONRBC count Grossly bloody or >100,000 cells/mm^3 suggests trauma,
malignancy, PE, pneumoniaNeutrophils >50% suggests acute pleural process (infection, PE).Lymphocytes >50% suggests chronic pleural process (TB, malignancy)Eosinophils Presence suggests air or blood in pleural space.Glucose <60 mg/dL suggests a complicated parapneumonic effusion,
malignancy, ruptured esophagus, TB, or rheumatoid arthritis.Triglycerides >110 mg/dL suggests chylothorax.pH Pleural pH <7.2 with parapneumonic effusion indicates the
need for drainage.TABLE 10.18. Common Causes of Secondary Spontaneous PneumothoraxCOPD (most common)
Asthma
Pneumonia (eg, PCP)
TB
Interstitial lung disease
Cystic fibrosis
Malignancy
Endometriosis