OBSTETRICS AND GYNECOLOGY
592
DIAGNOSIS
Confirm PROM with a sterile speculum exam showing:
■ A pool of fluid in the posterior fornix
■ A pH >6.5 (nitrazine paper turns blue!)
■ Ferning of fluid as it dries on a slide; this results from the presence of pro-
teins and electrolytes in the amniotic fluid and is also diagnostic
TREATMENT
■ Immediate OB consultation and admission
■ Test patients for chlamydia, gonorrhea, and group B streptococcus.
■ Prophylactic antibiotics to prevent anminonitis in patients with PROM is
controversial.
PREGNANCY-INDUCED HYPERTENSION
Pregnancy-induced hypertension is defined as BP >140/90 or an increase in
systolic BP >20 (or diastolic >10) above baseline.
Preeclampsia/Eclampsia
Preeclampsia is defined as the presence of new onset hypertension and pro-
teinuria with or without edema in women who are >20 weeks gestation.
Eclampsia = preeclampsia plus seizures.
Risk factors for preeclampsia include:
■ Primigravida
■ Very young or advanced maternal age
■ Diabetes mellitus
■ Multiple gestations
■ Hydatidiform mole
SYMPTOMS
■ Weight gain (>5 pounds/week)
■ Headache/visual disturbances
■ Extremity or facial swelling
■ Shortness of breath
■ Decreased urine output
EXAM
Usually a normal physical exam except for high blood pressure. Edema (peri-
pheral or facial) can be present.
DIFFERENTIAL
■ Gestational hypertension: Mild hypertension after 20 weeks gestation with
no proteinuria present; may progress to preeclampsia, but usually resolves
by 12 weeks postpartum
■ Chronic hypertension (aka preexisting hypertension): Defined as systolic
pressure≥140 mmHg, diastolic pressure ≥90 mmHg, or both, that antedates
pregnancy; present prior to the 20th week, or persists >12 weeks postpartum.
Usually treated with methyldopa (Aldomet), labetalol, or nifedipine;avoid
diuretics and ace inhibitors
Blue nitrazine paper +
ferning = amniotic fluid.
Never ignore an elevated BP
in a pregnant patient.
Eclampsia can kill both the
mother and fetus.