OBSTETRICS AND GYNECOLOGY
610VAGINAL BLEEDINGGynecologic causes of abnormal vaginal bleeding in nonpregnant, reproduc-
tive age females include: (1) ovulatory bleeding, (2) anovulatory bleeding, or
(3) nonuterine bleeding. (See Table 12.8.)SYMPTOMS/EXAM
■ Ovulatory bleeding is associated with menses and preceded by breast ten-
derness, abdominal bloating, and dysmenorrhea.
■ Anovulatory bleeding is seen mostly in perimenarchal or perimenopausal
women. In adolescents physical exam is usually normal. If blood loss is con-
siderable or lasting >9 days check coagulation studies. In perimenopausal
women, atrophic vaginitis is a common cause.
■ Nonuterine bleeding is vaginal bleeding. Bleeding from nose or gums sug-
gests systemic etiology. Vaginal lacerationsoccur following penile or foreign
body penetration and typically require suturing.DIFFERENTIAL
■ Ovulatory bleeding is due to pelvic diseases (PID, endometriosis, ovarian
neoplasm) or uterine causes (leiomyomas, polyps, endometrial malignancy,
or hyperplasia).
■ Anovulatory bleeding in adolescents is mostly due to immature hypothalamic-
pituitary-ovarian axis; in reproductive age, is usually due to fluctuating levels
or estrogen that go below a critical level needed to maintain the endo-
metrium. In menopausal patients, malignancy needs to be ruled out with an
endometrial biopsy.
■ Nonuterine bleeding can be from cervix or vagina. Consider also lower
urinary tract or GI bleeding.TABLE 12.8. Definitions of Vaginal BleedingAbnormal vaginal bleeding Occurs outside menstrual cycleMenorrhagia Menses > 7 days, or> 60-mL blood loss oroccurring
< every 21 daysMetrorrhagia Bleeding at irregular timesMenometrorrhagia Heavy irregular vaginal bleedingDysfunctional uterine bleeding Abnormal vaginal bleeding due to anovulationPostcoital bleeding Vaginal bleeding after intercourse suggesting cervical
pathologyPostmenopausal bleeding Any bleeding that occurs > 6 months after cessation of
menses