DIAGNOSIS
■ CT scan is notthe imaging of choice (is often normal).
■ Obtain angiography (CT angiogram has not been fully evaluated) and/or
MRI/MRA to confirm diagnosis.
TREATMENT
■ Surgical
■ Anticoagulation
Cerebral Venous Thrombosis
CAUSES
Causes include adjacent local infection, direct injury (eg, trauma) or hyperco-
agulable state (eg, pregnancy).
SYMPTOMS/EXAM
■ Symptoms are varied and often vague.
■ Headache is the most common presenting complaint.
■ Altered mental status, focal neurologic deficits, papilledema, or seizures
may occur.
DIAGNOSIS
■ CT and standard MRI scanning are useful only if positive (cannot exclude
the diagnosis).
■ Magnetic resonance venography (MRV) combined with MRIis imaging
modality of choice and has replaced angiography.
■ CT venography is being evaluated as a possible imaging method.
TREATMENT
■ Heparin
■ Catheter-based thrombolysis if severe symptoms
Post—Lumbar Puncture Headache
CAUSES
A post-LP headache develops within 24–48 hours of LP due to persistent CSF
leak from the LP puncture site.
SYMPTOMS/DIAGNOSIS
Headache that is worse with upright posture and improved with lying flat
TREATMENT
■ Simple analgesics
■ Intravenous fluids
■ Caffeine IV
■ Blood patch, if no relief with the above measures
NEUROLOGY
Caffeine IV can be very
effective in treating
post-LP headaches.