RENAL AND GENITOURINARY
EMERGENCIESACUTE BACTERIAL PROSTATITISETIOLOGY
■ Patients <35 years: Sexually transmitted pathogens C. trachomatis and/or
N. gonorrhoeae (GC)predominate.
■ Patients ≥35 years:Most often caused by Gram-negative organisms, pre-
dominantly E. coli. Mixed bacterial infections are uncommon. Suspect
anacute exacerbation of chronic prostatitisif there is a history of recur-
rent UTIs.
■ Tuberculosis should be considered in the presence of renal TB.SYMPTOMS/EXAM
■ Fever/chills.
■ Perineal or low back pain.
■ Urgency, dysuria, frequency, urinary retention.
■ Tender swollen prostate that is firm and warm to the touch (avoid prostatic
massage as it may precipitate bacteremia).DIAGNOSIS
■ Clinical examination is key to diagnosis.
■ Urine culture may help isolate organism.TREATMENT
■ Supportive care with analgesia, antipyretics, hydration.
■ Antibiotics:
■ Age <35 years: Ceftriaxone (IM ×1) or ofloxacin (×10 days) and doxy-
cycline (×10 days)
■ Age≥35 years: Fluoroquinolone or trimethoprim/sulfamethoxazole for
2–4 weeks
■ Chronic bacterial: Fluoroquinolone × 4 weeks or trimethoprim/
sulfamethoxazole for 1–3 months
■ Avoidurethral catheterization, use suprapubic catheter if urinary retention
occurs.
■ Parenteral antibiotics and admission if patient appears toxicPENILE ULCERSSexually transmitted diseases are the likely cause of isolated penile
ulcers. Table 18.9 outlines the organisms, diagnosis, and treatment. See
Figures 18.1–4.DIFFERENTIAL
■ In the setting of genital ulceration andoral ulcerations consider Behçet dis-
ease, Stevens-Johnson syndrome, Reiter syndrome, pemphigus vulgaris.
■ Others causes of isolated genital unceration include lymphoma, carci-
noma, vasculitis, fixed drug eruption, trauma.DIAGNOSIS
■ Diagnosis is often clinical.
■ Syphilis is diagnosed by dark-field examination, direct fluorescent antibody
testing, and serology.Prostatitis
<35 years: Think STD.
≥35 years: Think E. coli;
needs prolonged antibiotic
therapy.