Cell Biology: Cytoplasm 11349.A 22-year-old woman presents at the ophthalmology clinic. She
describes an initial inability to drive at night because of what she describes as
“night blindness.” She says that the deterioration of her vision has continued
and she is having difficulty seeing objects on the periphery of her vision.
Visual acuity, color, visual field, dark adaptation, and ERG testing is com-
pleted. The tests show rod degeneration with limited peripheral vision. She
has pigment deposits in the mid-peripheral retina known as “bone spicules”
She also has attenuated vessels in the retina and paleness of the optic nerves.
An electroretinogram (ERG) is reduced in amplitude. The cause may be
related to a failure of opsin and other protein vesicle transport. This transport
would occur along which of the following?
a. Microfilaments (thin filaments)
b. Thick filaments
c. Microtubules
b. Intermediate filaments
e. Spectrin heterodimers
50.Which of the following molecules forms the coating of vesicles involved in
transport of secretory vesicles from the trans-Golgi network (TGN) to targets?
a. Clathrin
b. Spectrin
c. Ankyrin
d. Actin
e. Vimentin
f. COP I
g. COP II