58.A 32-year-old (gravida 2, para 2) woman who gave birth to a baby girl
24 hours before is having difficulty urinating and is retaining urine in her
bladder. She is given bethanechol, a muscarinic agonist, which is the
ligand shown in the diagram below. Which of the following is the function
of molecule A?
130 Anatomy, Histology, and Cell Biology
(Modified, with permission, from Avery JK:Oral Development and Histology,3/e. New York:
Thieme Medical, 2001.)
a. Directly activates protein kinase C
b. Binds to the endoplasmic reticulum
c. Hydrolysis of PIP 2 to form DAG and IP 3
d. Stimulation of Giactivity through phosphorylation of PIP 2
e. Stimulation of GSactivity through phosphorylation of PIP 2